Results 71 to 80 of about 6,736,385 (301)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Caudate-right-lobe ratio in case of portal venous variants.

, 2018
In normal anatomy, the first bifurcation of the right portal vein (RPV) is used for the caudate-right-lobe ratio (CRL-R) calculation A), while anatomic variants are shown on the right side of the figure.
Roland Kreis (445470), Andreas Christe (403772), Adrian T. Huber (5497358), Johannes T. Heverhagen (343136), Verena C. Obmann (5497361), Lukas Ebner (403773), Annalisa Berzigotti (387331), Peter Vermathen (747029), Nando Mertineit (4021445), Christina Marx (5497364)   +9 more
core   +1 more source

Diagnostic accuracy of serum biomarkers to identify giant cell arteritis in patients with polymyalgia rheumatica

RMD Open
Introduction Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are frequently overlapping conditions. Unlike in GCA, vascular inflammation is absent in PMR.
Maxime Samson, Bernard Bonnotte, Karine Goueslard, Helene Greigert, André Ramon, Paul Ornetti, Sylvain Audia, Marion Ciudad, Jean Francis Maillefert, Claudie Cladière   +9 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Personal Papers (MS 80-0002)

, 1963
Report from National Right to Work Committee discussing the committee's activities and involvement around the ...
National Right to Work Committee
core  

Right-Wing Populism and Fascism

, 2019
Right-Wing Populism and Fascism: Resource MaterialsRight-Wing Populism in AmericaFascismNeofascismTrump ...
Chip Berlet (4709986)
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Nature of the Alt-Right

, 2018
The presidential campaign and eventual election of president Donald Trump emboldened and highlighted the existence of a fringe group known as the alt-right, short for alternative right.
Byron Williams (1915777), null null, Byron Williams   +2 more
core   +1 more source

Right Livelihood Annual Report 2021 [PDF]

, 2022
As we look back on 2021, we see a pivotal year behind us. Despite the Covid-19 pandemic, we were able to promote the work of Laureates worldwide, while also taking important steps towards developing Right Livelihood as an organisation.We were especially ...

core   +1 more source

Evaluation of dasatinib and ponatinib for the control of CD123 CAR-T cell functionalities

Molecular Therapy: Oncology
CD123 CAR-T cells (CAR123) represent a promising therapeutic approach for blastic plasmacytoid dendritic cell neoplasm (BPDCN) and CD123+ acute myeloid leukemia (AML).
Charles-Frédéric Mantion, Sabeha Biichlé, Xavier Roussel, Gwenaël Rolin, Agathe Lejeune, Tony Labaigt, Elodie Bôle-Richard, Etienne Daguindau, Bernard Royer, Florian Renosi, Olivier Adotevi, Romain Loyon, Maxime Fredon, Francine Garnache-Ottou   +13 more
doaj   +1 more source