Results 51 to 60 of about 360,286 (307)

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

4-Valve Heart Disease and Right Heart Failure [PDF]

Journal of Cardiothoracic and Vascular Anesthesia, 2018
Carcinoid heart disease is a rare form of heart disease due to secretion of vasoactive compounds, including serotonin, from gastrointestinal tumors. This E-challenge examines the case of a patient with advanced carcinoid heart disease who presented to the operating room (OR) for a tricuspid valve replacement.
Kathyrn Glas, McKenzie M. Hollon, Michele Sumler   +2 more
openaire   +2 more sources

Levosimendan in pulmonary hypertension and right heart failure [PDF]

Pulmonary Circulation, 2018
Pulmonary hypertension is a multifactorial disease with a high morbidity and mortality. Right ventricular function is the most important predictor of morbidity and mortality in patients suffering from pulmonary hypertension, but currently there are no approved treatments directly supporting the failing right ventricle.
Hansen, Mona Sahlholdt, Andersen, Asger, Nielsen-Kudsk, Jens Erik   +2 more
openaire   +4 more sources

Continuous Monitoring of Bladder Dysfunction in People With Multiple Sclerosis: Wearables for the Bladder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Bladder dysfunction affects over 85% of people with multiple sclerosis (PwMS), yet current assessment methods are limited to periodic in‐clinic evaluations or subjective patient reports, failing to capture real‐world symptom fluctuations.
Valerie J. Block, Shane Poole, Leah McIntyre, Nikki Sisodia, Chelyn Park, Gabby Joseph, Michelle E. Van Kuiken, Anne M. Suskind, Riley Bove   +8 more
wiley   +1 more source

Echocardiographic diagnosis, management and monitoring of pulmonary embolism with right heart thrombus in a patient with myotonic dystrophy: a case report

Cardiovascular Ultrasound, 2010
Acute pulmonary embolism (PE) is a common disease which frequently results in life-threatening right ventricular (RV) failure. High-risk PE, presenting with hypotension, shock, RV dysfunction or right heart thrombus is associated with a high mortality ...
Baumann Gert, Panda Alexander, Fallenberg Eva M, Dreger Henryk, Ghaeni Leyli, Hewing Bernd, Borges Adrian C   +6 more
doaj   +1 more source

Time trends and predictors of gout remission over six years

Arthritis Care &Research, Accepted Article.
Objectives This study aims to describe the trends in remission rates over six years of follow‐up among people with gout taking urate‐lowering therapy (ULT), and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES ...
Adwoa Dansoa Tabi‐Amponsah, Sarah Stewart, Greg Gamble, Lisa K Stamp, William J Taylor, Nicola Dalbeth   +5 more
wiley   +1 more source

Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support device

Therapeutic Advances in Cardiovascular Disease, 2020
Acute right heart failure is associated with impaired prognosis in cardiogenic shock. Since most pharmacological therapies are not evaluated for the failing right ventricle, or even contraindicated, there is a need for rapid minimal invasive circulatory ...
Markus W. Ferrari, P. Christian Schulze, Daniel Kretzschmar   +2 more
doaj   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Unusual right heart failure in a patient with heart transplant [PDF]

European Heart Journal, 2010
A 53-year-old man with a history of two heart transplantations in a context of Becker muscular dystrophy was admitted in our department with a 2-month history of moderate right-sided heart failure. He reported a stage 3 NYHA dyspnoea. Heart sounds were distant, with no murmurs, gallops, or rub. He presented peripheral oedema, hepatomegaly, …
Jerome Roncalli, Pauline Fournier, Marie-Agnès Marachet, Olivier Lairez   +3 more
openaire   +3 more sources

A retrospective observational study investigating the factors associated with right heart failure in patients with primary acute pulmonary embolism and deep vein thrombosis

Journal of General and Family Medicine, 2020
Background The relationship between the risk of right heart failure in primary acute pulmonary embolism after embolization and the residual thrombus sites in the pelvis and lower limbs is not clear.
Satoshi Kobayashi, Makoto Muto, Hitoshi Yabe, Masashi Imao, Yukinori Okada   +4 more
doaj   +1 more source