Results 121 to 130 of about 91,914,713 (247)
Right-To-Left and Left-To-Right characters
, 2007 There's been a fair bit of discussion going on at slackers on the security implications of the Unicode characters U+202D and U+202E which switch the left-to-right and right-to-left encoding of the following ...
Eve, Martin Paul
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The right to speedy trial [PDF]
, 1992 A more liberal notion of prejudice than that so far adopted by the Hong Kong courts should be accepted. Prejudice short of actual impairment of the right to defend oneself should suffice for the purpose of a finding of a violation of the right to speedy ...
Chan, Man-mun, Johannes
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Unguarded tricuspid orifice diagnosed by echocardiography: a clinical study
The Turkish Journal of Pediatrics, 2000 Complete absence of tricuspid valve tissue and apparatus with a normal orifice between the right atrium and the right ventricle is defined as "unguarded tricuspid orifice". Very few case report of this anomaly have appeared in the literature.
A Kiliç, S Ozkutlu, N Günal
doaj
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Why coronavirus is likely to be bad news for Europe’s radical right
, 2020 Published on 7 May 2020Even if coronavirus has a negative effect on public attitudes to immigration, it will be bad news for Europe’s radical right, argue Dr James Dennison and Professor Andrew Geddes.
DENNISON, James, GEDDES, Andrew
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Heart and chest veins in the rabbit [PDF]
Eurasian Journal of Veterinary SciencesIn this study, obtaining Gazi University, Department of Laboratory Animals 10 adult New Zealand rabbits(6 female, 4 male) were used as experimental animals. Colorized latex was injected to materials and materials were dissected and photographs were taken.
E. Ümran Bozkurt, Nejdet Dursun
doaj
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source