Results 111 to 120 of about 1,791,801 (336)

Reasons why people in Switzerland seek assisted suicide: the view of patients and physicians

Swiss Medical Weekly, 2009
M Furter, C Schwarzenegger, SJ Ziegler, Imhof Mahrer   +3 more
doaj   +1 more source

Transitional labour markets: A new European employment strategy [PDF]

Although it has become fashionable to reject full employment as a realistic objective for economic and social policy, there is one important reason to stick to this goal. Full employment always reflected the idea that all persons should have the right to
Schmid, Günther
core  

A Tale of Two \u3ci\u3eLochners\u3c/i\u3e: The Untold History of Substantive Due Process and the Idea of Fundamental Rights [PDF]

, 2009
To say that the Supreme Court\u27s decision in Lochner v. New York is infamous is an understatement. Scholars remember Lochner for its strong right to contract and laissez-faire ideals--at least that is the conventional account of the case.
Nourse, Victoria
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Limitação de esforço terapêutico na pessoa com lesão encefálica grave

Revista Bioética
As discussões a respeito das condutas de limitação de esforço terapêutico (LET) são frequentes nas unidades de terapia intensiva e na especialidade médica oncológica e são também importantes em contextos hospitalares de internação de longa permanência ...
Henrique de Alencar Gomes, Mônica Adelaide Almeida, Terezinha Valéria Ferreira Matoso, Maria Angélica Assunção Viana, Maria Bernadete Cardoso Rezende, Maíza Ângela Ferreira Bento, Tatiane Santos Fonseca Guimarães, Sabrina Vilane de Oliveira Alcântara, Ary Demétrio Júnior, Ana Paula Gomes Costa Silva, Cibele Renata de Paula Moreira, Daniela Simplício Vieira Albergaria, Marília Káthya Coutinho, Marli Medeiros, Roseli Melo Silva de Souza, Polianna Cristina Pires Dumont   +15 more
doaj   +1 more source

The right to live in peace … and to die in peace as well

, 2020
Verónica Rojas, Ariel Pasmiño, A. Palma   +2 more
openalex   +2 more sources

Economic interests and the origins of electoral systems [PDF]

Die gängige Begründung – basierend auf der bahnbrechenden Arbeit Rokkans – dafür, dass ein spezifisches Wahlsystem bevorzugt wird, ist, dass die Verhältniswahl („proportional respresentation“ oder „PR“) von einer zersplitterten Rechte eingeführt wurde ...
Cusack, Thomas R., Iversen, Torben, Soskice, David   +2 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

What Kind of a Right is the ‘Right to Die’?

European Journal of Mental Health, 2009
Constance E. Putnam
doaj   +3 more sources