Results 121 to 130 of about 1,765,259 (347)

Proxy voting in the joint stock company and the limited liability company [PDF]

open access: yes, 2010
Die Ausübung des Stimmrechts durch einen Stellvertreter stellt eine Möglichkeit für einen Aktionär oder einen Gesellschafter dar, sein Stimmrecht auch dann auszuüben, wenn er nicht persönlich an der Haupt- bzw.
Lieberam-Schmidt, Sabine
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Euthanasia and complacency in bioethics: an approach based on suicide [PDF]

open access: yes, 2017
Advocates o euthanasia advocate the "right to die with dignity and recently with the pressures of life in society claim "the duty to die".
Serrano Ruiz-Calderón, José Miguel
core  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Reasons why people in Switzerland seek assisted suicide: the view of patients and physicians

open access: yesSwiss Medical Weekly, 2009
M Furter   +3 more
doaj   +1 more source

Limitação de esforço terapêutico na pessoa com lesão encefálica grave

open access: yesRevista Bioética
As discussões a respeito das condutas de limitação de esforço terapêutico (LET) são frequentes nas unidades de terapia intensiva e na especialidade médica oncológica e são também importantes em contextos hospitalares de internação de longa permanência ...
Henrique de Alencar Gomes   +15 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

The Right to Die Debate: A Survey [PDF]

open access: bronze, 2001
Rosangela Barcaro
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

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