Results 171 to 180 of about 4,155,575 (342)

Math goes to Hollywood: Stereotypen in Filmen und Serien dekodieren [PDF]

open access: yesarXiv
Stereotype Vorstellungen von Mathematik und Mathematiker*innen beeinflussen das Interesse von Jugendlichen an MINT-F\"achern. Daher pl\"adiert dieser Beitrag daf\"ur, popul\"are Filme und erfolgreiche Serien nicht nur im Fremdsprachenunterricht, sondern auch im Mathematikunterricht einzusetzen.
arxiv  

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

The Last Right: Australians take sides on the right to die [PDF]

open access: yes, 2014
This is the text of an out-of-print book first published in 1995 by Mandarin Books, Port Melbourne. Edited by Professors Simon Chapman and Stephen Leeder, it features contributions from 63 prominent Australians both supportive and opposed to voluntary ...
Chapman, Simon, Leeder, Stephen R
core  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

What Kind of a Right is the ‘Right to Die’?

open access: yesEuropean Journal of Mental Health, 2009
Constance E. Putnam
doaj   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

Suicide assisted by two Swiss right-to-die organisations

open access: yesJournal of Medical Ethics, 2008
S. Fischer   +6 more
semanticscholar   +1 more source

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