Results 91 to 100 of about 4,344,934 (307)
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
COVID-19 and the right to education in Chile: An opportunity to revisit our social contract. [PDF]
Gelber D +4 more
europepmc +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Disestablishing Local School Districts as a Remedy for Educational Inadequacy Note [PDF]
Most state constitutions recognize a right to education, but courts have been hard pressed to respond to violations of that right. Some state courts have imposed financial and substantive reforms, only to see their implementation miscarry as educational ...
Saiger, Aaron J.
core +2 more sources
The conflict in Ukraine has led to the displacement of millions of children and their mothers, posing an unprecedented challenge to host countries such as Spain.
Sandra Lorente-Avilés +2 more
doaj +1 more source
Right to education in South Darfur [PDF]
Education is an absolute right for all children, yet in Darfurchildren have always had limited access to schooling.Innovative programmes and increased assistance arevital if children in South Darfur are to exercise this right.
Katherine Reid
doaj
HAK ASASI MANUSIA SEBAGAI JUS COGENS DAN KAITANNYA DENGAN HAK ATAS PENDIDIKAN
Jus cogens as a norm of general international law accepted and recognized by the community as a whole interasional with the main characteristics are non-derogable nature.
Virgayani Fattah
doaj +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Right to Education (RTE) Act, 2009 and Private School Closure in India [PDF]
In recent years, there have been reports in the media, that due to the implementation of the Right to Education Act 2009, many private schools have been closed down and many more will be closed down.
core
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source

