Results 61 to 70 of about 46,167 (258)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Small Claims in Civil Procedure in Ukraine: Panacea or an Obstacle to Access Justice

open access: yesRevista Jurídica Portucalense, 2023
One of the directions of development of civil procedure of  the majority of the world is the differentiation of civil  proceedings, in particular, through the introduction of various simplified proceedings.
Yurii PRYTYKA, Serhii KRAVTSOV
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

THE PREVALENCE OF LEGAL CERTAINTY WITHIN THE SCOPE OF FAIR TRIAL: POSSIBILITY OF MITIGATION OF PRECLUSION IN FAVOR OF THE FUNDAMENTAL RIGHT TO PROOF

open access: yesRevista Eletrônica de Direito Processual, 2017
The purpose of this study is to examine the constitutional status of the right to proof, as well as its prevalence in relation to infra-constitutional legislation, especially in view of the procedural norms of preclusion.
Fernando Rubin, Gustavo Mascarello Silva
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Protection of the Right to a Fair Trial within a Reasonable Time: Case Law of the European Court of Human Rights and an experience of foreign countries

open access: yesТеорія і практика правознавства, 2016
In the article with the requirements of Art. 6 (§1), Art. 13 of the ECHR and case law of the European Court of Human Rights author reviews questions related to obligation of the state to ensure the existence of effective legal remedies for the protection
Т. А. Цувіна
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Fair Trial and the Principles Governing It Internationally and Domestically Focusing on Governmental Discretionary Punishment [PDF]

open access: yesپژوهش‌نامۀ انتقادی متون و برنامه‌های علوم انسانی, 2018
The two terms "fair trial" and "statecraft and the principles of justice" were taken in the same sense and have been used interchangeably. No one should be deprived of his life, liberty, and property without a fair trial.
Ahmad Asadian, Jahanbakhsh Salariyan
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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