Results 81 to 90 of about 794,785 (306)

The approach of the European court of human rights to environmental protection [PDF]

open access: yes, 2006
The thesis aims to analyse the protection of environmental interests through the cases decided by the European Convention of Human Rights. The Convention does not include a right to a healthy environment.
Savaresi, Annalisa
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Small Claims in Civil Procedure in Ukraine: Panacea or an Obstacle to Access Justice

open access: yesRevista Jurídica Portucalense, 2023
One of the directions of development of civil procedure of  the majority of the world is the differentiation of civil  proceedings, in particular, through the introduction of various simplified proceedings.
Yurii PRYTYKA, Serhii KRAVTSOV
doaj  

THE PREVALENCE OF LEGAL CERTAINTY WITHIN THE SCOPE OF FAIR TRIAL: POSSIBILITY OF MITIGATION OF PRECLUSION IN FAVOR OF THE FUNDAMENTAL RIGHT TO PROOF

open access: yesRevista Eletrônica de Direito Processual, 2017
The purpose of this study is to examine the constitutional status of the right to proof, as well as its prevalence in relation to infra-constitutional legislation, especially in view of the procedural norms of preclusion.
Fernando Rubin, Gustavo Mascarello Silva
doaj   +1 more source

Grounding procedural rights [PDF]

open access: yes, 2019
Contrary to the widely accepted consensus, Christopher Heath Wellman argues that there are no pre-institutional judicial procedural rights. Thus commonly affirmed rights like the right to a fair trial cannot be assumed in the literature on punishment and
Adams, N. P.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Забезпечення реалізації права на здоров'я в діяльності Європейського суду з прав людини [PDF]

open access: yes, 2012
Сажієнко Н. В. Забезпечення реалізації права на здоров'я в діяльності Європейського суду з прав людини /Н. В. Сажієнко // Актуальні проблеми політики : зб. наук. пр. / редкол. : С. В. Ківалов (голов. ред..), Л. І. Кормич (заст. голов. ред..), Ю.
Sazhienko, N.   +2 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

'Mad' Edwin Withers and the Struggle for Fair Trial Rights in NSW [PDF]

open access: yes, 2016
Since the 1980s, a number of fair trial rights and civil liberties have been eroded in Australia, particularly in respect to summary justice and police powers.
Schofield-Georgeson, E
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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