Results 61 to 70 of about 136,266 (300)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

El derecho a la vivienda en Argentina: una mirada desde el Derecho Administrativo español

open access: yesRevista Vasca de Administración Pública, 2019
In the Argentinean constitution, the right to decent and adequate housing is expressly covered as a subjective right judicially enforceable. In its implementation, the several levels of the Administration have acknowledged very broadly the right to ...
Alejandra Boto Álvarez
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

As políticas habitacionais e as ocupações urbanas: dissenso na cidade

open access: yesCadernos Metrópole
Resumo O artigo trata do enfrentamento cotidiano no acesso ao direito à moradia e à cidade. Como pano de fundo do debate teórico, têm-se as ocupações urbanas em contraponto aos empreendimentos do Programa Minha Casa Minha Vida em Belo Horizonte, diante ...
Denise Morado Nascimento
doaj   +1 more source

The 'Right to Housing' for Homeless People

open access: yes, 2010
FEANTSA has a longstanding commitment to ‘a rights-based’ approach to tackling homelessness, and this commitment is shared by many working in the homelessness field.
Fitzpatrick, Suzanne; id_orcid   +1 more
core  

Alternative housing

open access: yes, 2022
Our societies are evolving at a rapid pace, challenging the certainties of the past. Two fundamental changes stand out, and raise questions concerning housing.
Ledent, Gérald   +1 more
core  

The legacy of the Right to Buy and the differentiation of older home owners [PDF]

open access: yes, 2020
This paper explores older owner occupiers in lower value properties who, having acquired their home through the Right to Buy (RTB) in the 1980s, are now experiencing housing-related challenges in older age.
Satsangi, Madhu   +2 more
core   +1 more source

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