Results 61 to 70 of about 136,832 (300)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Homeless women’s path towards social inclusion: an analysis of social housing models in Italy [PDF]
, 2022 openHomelessness represents a growing phenomenon and a serious violation of the right to adequate housing. The recent urban modernisation, the organisation of sporting events and the frequent migration flows have worsened the housing situation, which ...
LIO, MIRANDA
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Le balene sconfiggono i confini. Appunti per una narrazione fra storie familiari e spazi urbani
Cambio, 2016 The article is an ethnographic text and it concerns those people that the society defines “marginal”, “excluded” or “poor”; notions used in a critical approach. The narrative discourse used is the expression of the narrative mode of thinking that «deals -
Sabrina Tosi Cambini
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Mobilising anti-discrimination law to defend housing rights in Europe: Socioeconomic disadvantage and the right to housing [PDF]
, 2017 This paper focuses on socioeconomic disadvantage as a significant source of inequality in the realm of housing. Taking into account international and European human rights law, as well as selected domestic systems, it will show how anti-discrimination ...
Benito Sanchez, Juan Carlos +1 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The Voluntary Right to Buy pilot: Additional analysis of completions [PDF]
, 2017 This report builds on detailed analysis of the lessons from the pilot programme for the Voluntary Right to Buy (VRTB). The introduction of the right to buy (RTB) for eligible tenants in specified housing association dwellings was a manifesto commitment ...
Reeve, Kesia, Pattison, Ben, Cole, Ian
core
Self-build in the UK and Netherlands:mainstreaming self-development to address housing shortages? [PDF]
, 2015 This paper examines approaches to self or custom-build in the Netherlands and the UK to offer comparative insights into self- and custom-built housing contexts and cultures, and specifically, the relationships with local and strategic planning ...
Lloyd, M.G. +8 more
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source