Results 71 to 80 of about 130,293 (294)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Addressing the Housing Crisis: Insights from a Study on University Students in Turkey

Social Welfare: Interdisciplinary Approach
Housing stands as a fundamental human right, acknowledged by numerous international bodies and statutes. Despite this recognition, only a handful of nations ensure adequate housing for their populace.
Doğa Başar Sarıipek, Zahide Peker, Gökçe Cerev   +2 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Housing as a Social Security Instrument to Overcome Homelessness

İstanbul Üniversitesi Sosyoloji Dergisi
Homelessness is a spatial manifestation of social insecurity. Housing, a means of satisfying the need for shelter, is also an instrument of social security.
Hicran Atatanır
doaj   +1 more source

The rights we live in: protecting the right to housing in Spain through fair trial, private and family life and non-retrogressive measures

, 2016
This article offers a two-line strategic approach to tackle the housing crisis in Spain from a human rights perspective. First, it advocates changes to the mortgage repossession procedure based on the principles of proportionality and reasonableness of ...
Koldo Casla
semanticscholar   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Conditions for Exercise by Foreign Citizens of Some Fundamental Social Rights as Subjective Rights

Теоретическая и прикладная юриспруденция, 2019
With a high migration attractiveness of Russia, the issue of the exercise of fundamental social rights by foreigners, including minors, in Russiа is important. The author reviewed the existing regulations, enshrining the right to health and medical care,
A. I. Petrova
doaj  

The Right to Housing and the Powers of the State [PDF]

Revista d'Estudis Autonòmics i Federals
The supposedly exclusive powers of the Spanish autonomous communities on housing are strongly conditioned by the concurrent powers of the State. The interpretation of these powers made by the Spanish Constitutional Court has prioritised the objective ...
Marcos Vaquer Caballería
doaj   +1 more source