Results 101 to 110 of about 2,576,175 (309)

Department of Health Commissioner – Correspondence, 1990-1991 and 1993-1995

open access: yes, 1990
Correspondence between Rick Engler and several government representatives, mainly commissioners from the Department of Health, concerning the Worker and Community Right to Know Act.

core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The genealogical jigsaw puzzle - a missing piece? the right to know for A.I.D. children [PDF]

open access: yes, 2004
This paper examines current UK legal regulation relating to the provision of genetic background information to children born by donor insemination (Dl) and argues in favour of changes to the existing law - the Human Fertilisation and Embryology Act 1990.
Henaghan, Caroline
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Right to information and freedom of expression [PDF]

open access: yes, 2004
Describes the important initiatives in Freedom of Expression in selected countries and Library Associations like IFLA and ILA. Indian initiaves in this direction aslo described and the need of strong involvement from Library associations and library ...
Vijayakumar, Manju, Vijayakumar, J. K.
core  

Information disorder. Learning to recognize fake news

open access: yes, 2022
The advent of the internet and digital platforms has revolutionised the way information is produced and disseminated. The aim of this paper was to examine whether it is possible to draw from Article 21 of the Italian Constitution that there is a right ...
Laura Lorello
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Firefighters - Use of Right-to-Know information [public presentation] December 17, 2001

open access: yes, 2001
This document contains presentation slides, survey materials, and fact sheets, relating to firefighters use of right to know ...

core  

Shareholders’ rıght to obtaın and examıne ınformatıon in joınt stock companıes in Turkısh law

open access: yesЮридический вестник Самарского университета
In joint stock companies, shareholders have the right to request information from the board of directors and auditors regarding the affairs of the company and to examine the company records when necessary.
Юнус Эмре Ай
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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