Results 131 to 140 of about 868,065 (299)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Las protestas sociales y el Derecho a la Resistencia en la Constitución del 2008.

, 2017
El presente trabajo de investigación aborda un tema de trascendental importancia para la defensa de la democracia constitucional: el derecho a la resistencia y una de sus principales expresiones la protesta social, entendido como una garantía social de ...
López Guerrero, Bertha Libia
core  

The Right to Resist and the Right of Rebellion

Jurisprudence, 2014
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Caso “Los diez de Luluncoto” y el Derecho a la Resistencia en el Estado Constitucional de Derechos y Justicia, año 2012

, 2017
La Constitución de la República del Ecuador en su artículo primero prescribe que el Ecuador es un Estado Constitucional de derechos y justicia; lo que implica garantizar todos y cada uno de los derechos plasmados en este cuerpo normativo.
Trávez Trávez, Myriam Alexandra
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Derecho a la resistencia y la lucha de la ECURUNARI en el ejercicio de este derecho, en un Estado Constitucional de Derechos, en la ciudad de Quito, en el año 2015

, 2017
El Derecho a la Resistencia en el Ecuador se encuentra establecido en la Constitución de Montecristi del año 2008, en el Art. 98.- en el que manifiesta lo siguiente: Los individuos y los colectivos podrán ejercer el derecho a la resistencia frente a ...
Pilco Villa, Alicia Verónica
core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Contribution of a specific panel by flow cytometry for the differential diagnosis of plasmacytoid dendritic cell neoplasms

Annals of Hematology
Florian Renosi, Sabeha Biichlé, Xavier Roussel, Thomas Fournet, Anne Roggy, Valentin Pourchet, Jean Francis Berry, Maxime Fredon, Margaux Poussard, Vahid Asnafi, Elizabeth Macintyre, Claude Preudhomme, Christophe Roumier, Eric Deconinck, Etienne Daguindau, Olivier Adotévi, Fanny Angelot-Delettre, Francine Garnache-Ottou   +17 more
doaj   +1 more source

Case Report: Dynamic TKI combination strategies for EGFR-mutant NSCLC with acquired ROS1 fusion and brain metastases. [PDF]

Front Oncol
Yang H, Da Y, Shen G, Sun QY, Yao ZY, Zhou YJ.   +5 more
europepmc   +1 more source