Results 111 to 120 of about 868,065 (299)

Derecho a la resistencia : limitaciones y problemática de su ejercicio legítimo. [PDF]

open access: yes, 2019
La Constitución del 2008 incorporó en el artículo 98 el derecho a la resistencia, que si bien es un derecho moral y propio de la naturaleza del ser humano, al estar reconocido en la Carta Magna se vuelve el deber del Estado –en virtud del artículo 11 ...
Barberán Flores de Valgas, Gema Nataly   +1 more
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The Right to Resistance and the Western Sahara: A Twail Analysis of the International Legal Order and Its Constraints on Decolonization

open access: yes
The Western Sahara is often called the Last Colony in the World, in reference to its anachronistic status as a territory deemed to have self-determination by the United Nations and ICJ, but still under the rule of another country.
Wrapp, Christina
core   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Право на спротив як форма реалізації реального народовладдя

open access: yes, 2018
Гайду А. В. Право на спротив як форма реалізації реального народовладдя / А. В. Гайду // Актуальні проблеми політики : зб. наук. пр. / редкол.: С. В. Ківалов (голов. редкол.), Л. І. Кормич (голов. ред.), А. В. Полухіна (відп.
Haidu, Anna V.   +3 more
core   +1 more source

El Ejercicio al Derecho a la Resistencia como Garantía Constitucional Extrainstitucional en el Nuevo Constitucionalismo Latinoamericano

open access: yes, 2022
The right to resistance has not reached a normative development that allows identifying the limits of its exercise, so much so that its application can be carried out in a normative framework that allows the individual or the community to act with the ...
Ajila Armijos, Danny Javier   +1 more
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Imprecisiones respecto al Derecho a la Resistencia en el Ecuador

open access: yes, 2013
The right to resistance, a right exercised in significant events such as the French Revolution was, for the first time, recognized in Ecuador through the Constitution approved in 2008.
Ramos Rosas, María Nazaret   +1 more
core   +2 more sources

The right of resistance in French renaissance

open access: yesKriterion, 2006
In the half of sixteenth century, with the increase of religious conflicts in the French kingdom, the political resistance issue retook an important place in public debate.
Alberto Ribeiro G. de Barros
doaj  

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

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