Results 91 to 100 of about 868,065 (299)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Refinement of the Co-Content function, through an integration of a polynomial fit of $$I-{I}_{sc}$$ I - I sc . Part 2 application to experimental current–voltage curves

Discover Electronics
In this article Part 2 of this series of articles, the methodology proposed in Part 1, namely, the fitting to a polynomial of the current minus the short-circuit current, i.e., $$I-{I}_{sc}$$ I - I sc , to calculate the Co-Content function $$\left(CC ...
Victor-Tapio Rangel-Kuoppa
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

On the right to resistance in kant*

, 2018
El empleo del derecho a la resistencia no tiende de alguna manera a realizar las aspiraciones populares, sino a defender o restaurar el orden establecido, por tanto, al reconocer el derecho de resistencia se pretende que sea un medio para que el príncipe
Vera Diaz, Adriana Constanza
core  

Problem tyranii w radykalnej myśli prezbiteriańskiej. Przypadek Samuela Rutherforda

, 2019
 The article delves into the principles of the right to resistance in radical Presbyterian thought. As an example, the author discusses Samuel Rutherford’s political theology, which represents a consummation of the earlier concepts of tyranny and ...
Tulejski , Tomasz, Tulejski, Tomasz
core   +2 more sources

Constitutional Regulation of the State of Exception in a Rechtsstaat [PDF]

, 2021
Název diplomové práce, abstrakt a klíčová slova v anglickém jazyce Title Constitutional Regulation of the State of Exception in a Rechtsstaat Abstract This treatise focuses on extraordinary reactive legal instruments designed for crises resolution, which
Kollert, Lukáš
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

KANT: MORALITY AND THE RIGHT TO RESISTANCE

, 1996
Čitava Kantova filozofija premašila je vlastite (humeovske) zarade racionalnog empirizma, dakle relativizma. Na planu morala taj relativizam je osobito nepoželjan, otud filozofija a priori pojmova; pravo kao minimum morala bio bi negiran političkim ...
Kurtović, Šefko, Šefko Kurtović
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

The Right to Resistance in Occupied Territory

, 2005
Resistance movements in occupied territory have been accepted as a concept since WWII. However, the exact characteristics of these movements and which rules apply to them, their rights and duties, have never been really clear.
Skygge, Ebba
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