Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Left Ventricular Pacing In Patients With Congestive Heart Failure [PDF]
, 2006 Cardiac resynchronisation therapy (CRT) using biventricular (BIV) pacing has proved its effectiveness to correct myocardial asynchrony and improve clinical status of patients with severe congestive heart failure (CHF) and widened QRS. Despite a different
Etienne, Yves +2 more
core
Pulmonary Hypertension, Right Ventricular Failure, and Vasodilator Therapy [PDF]
, 1986 Fidel Davila
openalex +1 more source
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
Advanced Science, EarlyView.In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
8Pre-existing right ventricular paced heart failure patients upgraded to cardiac resynchronisation therapy devices: a retrospective assessment of the functional and clinical benefits [PDF]
, 2017 N. A. Estes Mark
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Discovering Interpretable Semantics from Radio Signals for Contactless Cardiac Monitoring
Advanced Science, EarlyView.This study presents a semantic representation framework for clinically interpretable cardiac monitoring from contactless radio signals. It formulates radio semantic learning as an information‐bottleneck problem and approximates the objective via intra‐modal compression and cross‐modal alignment, structuring radio measurements into meaningful semantic ...
Jinbo Chen +10 more
wiley +1 more source
Idiopathic Submitral Left Ventricular Aneurysm: an Unusual Substrate for Ventricular Tachycardia in Caucasians [PDF]
, 2005 Annular submitral aneurysms have been rarely reported in Caucasians. They are typically diagnosed in non-white adults who present with severe mitral regurgitation, heart failure, systemic embolism, ventricular arrhythmias, and sudden cardiac death.
Arash, Arya +3 more
core
Advanced Science, EarlyView.This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab +14 more
wiley +1 more source
Right Ventricular Failure Following Left Ventricular Assist Device Implantation
, 2020 Niraghatam Harshavardhan +1 more
openalex +2 more sources
PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping
Advanced Science, EarlyView.scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su +7 more
wiley +1 more source