Results 201 to 210 of about 311,910 (353)

3'UTR Mapping Reveals Alternative Polyadenylation in Right Ventricular Failure. [PDF]

open access: yesCirc Res
Neupane R   +10 more
europepmc   +1 more source

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma   +2 more
wiley   +1 more source

Age and gender effects on echocardiographic and histopathological cardiac phenotypes in healthy adult mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study investigated the impact of age and sex on cardiac phenotypes in healthy adult C57BL/6J mice using echocardiography and histopathological analyses. Findings revealed that female mice demonstrated more pronounced global cardiac chamber dilation during aging.
Shuang Wen   +6 more
wiley   +1 more source

The utility of echocardiographic right ventricular parameters in predicting response to cardiac resynchronization therapy in patients with heart failure: A proof of concept

open access: diamond, 2019
Mokhtar Ibrahim   +99 more
openalex   +1 more source

Right ventricular exclusion procedure for right ventricular failure of Ebstein's anomaly [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2009
Cho, Sungkyu   +3 more
openaire   +2 more sources

A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions

open access: yesAnimal Models and Experimental Medicine, EarlyView.
To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang   +7 more
wiley   +1 more source

Ketone bodies in right ventricular failure: A unique therapeutic opportunity. [PDF]

open access: yesHeliyon, 2023
Blake M   +7 more
europepmc   +1 more source

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