Results 21 to 30 of about 566,258 (390)

The complement C3-complement factor D-C3a receptor signalling axis regulates cardiac remodelling in right ventricular failure

Nature Communications, 2022
Failure of the right ventricle plays a critical role in any type of heart failure. However, the mechanism remains unclear, and there is no specific therapy.
S. Ito, H. Hashimoto, Hiroyuki Yamakawa, D. Kusumoto, Y. Akiba, Takahiro Nakamura, M. Momoi, Jin Komuro, Toshiomi Katsuki, Mai Kimura, Yoshikazu Kishino, S. Kashimura, Akira Kunitomi, M. Lachmann, M. Shimojima, G. Yozu, Chikaaki Motoda, Tomohisa Seki, Tsunehisa Yamamoto, Y. Shinya, T. Hiraide, M. Kataoka, Takashi Kawakami, Kunimichi Suzuki, Kei Ito, Hirotaka Yada, M. Abe, M. Osaka, Hiromi Tsuru, Masayuki Yoshida, Kenji Sakimura, Y. Fukumoto, M. Yuzaki, K. Fukuda, S. Yuasa   +34 more
semanticscholar   +1 more source

Ventricular and Atrial Pressure—Volume Loops: Analysis of the Effects Induced by Right Centrifugal Pump Assistance

Bioengineering, 2022
The main indications for right ventricular assist device (RVAD) support are right heart failure after implantation of a left ventricular assist device (LVAD) or early graft failure following heart transplantation.
Beatrice De Lazzari, Attilio Iacovoni, Massimo Capoccia, Silvia Papa, Roberto Badagliacca, Domenico Filomena, Claudio De Lazzari   +6 more
doaj   +1 more source

Right ventricular failure after left ventricular assist device implantation: a review of the literature

Journal of Thoracic Disease, 2021
Right ventricular failure (RVF) following left ventricular assist device (LVAD) implantation remains a major complication which may significantly impair patient outcome. The genesis of RVF is, however, multifactorial, and the mechanisms underlying such a
V. Lo Coco, M. D. De Piero, Giulio Massimi, Giovanni Chiarini, G. Raffa, M. Kowalewski, J. Maessen, R. Lorusso   +7 more
semanticscholar   +1 more source

Right heart failure after left ventricular assist device: From mechanisms to treatments

Frontiers in Cardiovascular Medicine, 2022
Left ventricular assist device (LVAD) therapy is a lifesaving option for patients with medical therapy-refractory advanced heart failure. Depending on the definition, 5–44% of people supported with an LVAD develop right heart failure (RHF), which is ...
Claudio A. Bravo, Andrew G. Navarro, Karanpreet K. Dhaliwal, Maziar Khorsandi, Jeffrey E. Keenan, Parvathi Mudigonda, Kevin D. O'Brien, Claudius Mahr   +7 more
doaj   +1 more source

One-year outcomes after transcatheter insertion of an interatrial shunt device for the management of heart failure with preserved ejection fraction [PDF]

, 2016
Background—Heart failure with preserved ejection fraction has a complex pathophysiology and remains a therapeutic challenge. Elevated left atrial pressure, particularly during exercise, is a key contributor to morbidity and mortality.
Bergmann, Martin, Burkhoff, Dan, Doughty, Robert, Feldman, Ted, Hasenfuß, Gerd, Hausleiter, Jorg, Hayward, Christopher, Jondeau, Guillaume, Kaye, David M., Kolodziej, Adam, Muller, David, Neuzil, Petr, Penicka, Martin, Petrie, Mark C., Ponikowski, Piotr, Post, Martijn C., Raake, Philip, Rosenberg, Mark, Silvestry, Frank E., Trochu, Jean-Noël, van Veldhuisen, Dirk J., Walters, Darren, Walton, Antony, Westenfeld, Ralf   +23 more
core   +9 more sources

Sacubitril/valsartan in the treatment of systemic right ventricular failure

Heart, 2021
Objective Pharmacological options for patients with a failing systemic right ventricle (RV) in the context of transposition of the great arteries (TGA) after atrial switch or congenitally corrected TGA (ccTGA) are not well defined.
T. Zandstra, M. Nederend, M. Jongbloed, P. Kiès, H. Vliegen, B. Bouma, L. Tops, M. Schalij, A. Egorova   +8 more
semanticscholar   +1 more source

Post-operative Right Ventricular Failure After Cardiac Surgery: A Cohort Study

Frontiers in Cardiovascular Medicine, 2021
Introduction: Right ventricular failure (RVF) after cardiac surgery is an important risk factor for morbidity and mortality. Its diagnosis is challenging, and thus, its incidence and predictors are not well-established.
D. Levy, D. Laghlam, P. Estagnasié, A. Brusset, P. Squara, L. Nguyen   +5 more
semanticscholar   +1 more source

Right ventricular reserve post mitral valve repair is associated with heart failure hospitalization

Pulmonary Circulation, 2020
Right ventricular impairment is a predictor of cardiovascular outcomes in patients with degenerative mitral regurgitation. However, the time course of right ventricular functional changes post-surgical mitral valve repair remains largely unknown. Herein,
Wei-Ting Chang, Nan-Chun Wu, Jhih-Yuan Shih, Chih-Hsin Hsu, Zhih-Cherng Chen, Bor-Chih Cheng   +5 more
doaj   +1 more source

Right ventricular global dysfunction score: a new concept of right ventricular function assessment in patients with heart failure with reduced ejection fraction (HFrEF)

Frontiers in Cardiovascular Medicine, 2023
BackgroundRight ventricular (RV) function is currently being evaluated solely according to the properties of RV myocardium. We have tested a concept that in patients with heart failure with reduced ejection fraction (HFrEF), RV assessment should ...
Jan Benes, Martin Kotrc, Peter Wohlfahrt, Katerina Kroupova, Marek Tupy, Josef Kautzner, Vojtech Melenovsky   +6 more
doaj   +1 more source

What role does the right side of the heart play in circulation? [PDF]

, 2006
Right ventricular failure (RVF) is an underestimated problem in intensive care. This review explores the physiology and pathophysiology of right ventricular function and the pulmonary circulation.
Cecconi, M, Johnston, E, Rhodes, A
core   +2 more sources