Results 61 to 70 of about 311,910 (353)

Alterations in Dystrophin-Related Glycoproteins in Development of Right Ventricular Failure in Rats

Journal of Pharmacological Sciences, 2009
Genetic depletion of the dystrophin-related glycoprotein (DRGP) complex causes cardiomyopathy in animals and humans. The present study was undertaken to explore the possible involvement of alterations in DRGP in the development of the right ventricular ...
Takuya Daicho, Yoriko Daisho, Suguru Kojima, Saori Takano, Yugo Tejima, Tetsuro Marunouchi, Norio Takagi, Satoshi Takeo, Kouichi Tanonaka   +8 more
doaj   +1 more source

Early postoperative interventional ASD-closure for severe atrial right to left shunt in a neonate with common arterial trunk [PDF]

, 2013
Although closure of an atrial septal defect (ASD II) with an occluding device in the first year of life is not a routine procedure, it is a feasible treatment, even in neonates.
Dilber, Daniel, Eicken, Andreas, Hess, John   +2 more
core   +1 more source

Lack of right ventricular hypertrophy is associated with right heart failure in patients with left ventricular failure

Heart and Vessels, 2022
Presence of right heart failure (RHF) is associated with a worse prognosis in patients with left ventricular failure (LVF). While the cause of RHF secondary to LVF is multifactorial, an increased right ventricular (RV) afterload is believed as the major cause of RHF. However, data are scarce on the adaptive responses of the RV in patients with LVF. Our
Abdulrahman Naser, Tolga Sinan Güvenç, Khagani Isgandarov, Ahmet Ekmekçi, Sabahattin Gündüz, Rengin Çetin Güvenç, Müslüm Şahin   +6 more
openaire   +2 more sources

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Regulation of the Immune Microenvironment by an NLRP3 Inhibitor Contributes to Attenuation of Acute Right Ventricular Failure in Rats with Pulmonary Arterial Hypertension

Journal of Inflammation Research, 2021
Lizhe Guo,1 Gang Qin,1 Yanan Cao,1 Yue Yang,1 Sisi Dai,1 Lu Wang,1 E Wang1,2 1Department of Anesthesiology, Xiangya Hospital Central South University, Changsha, People’s Republic of China; 2National Clinical Research Center for Geriatric Disorders ...
Guo L, Qin G, Cao Y, Yang Y, Dai S, Wang L, Wang E   +6 more
doaj  

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

The failing heart under stress: echocardiography is an essential monitoring tool in the Intensive Care Unit [PDF]

, 2006
A
Poelaert, Jan
core   +2 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

A case report: corheart 6 biventricular assist device therapy for end-stage heart failure in dilated cardiomyopathy

Frontiers in Cardiovascular Medicine
Approximately one-third of patients with end-stage heart failure (ESHF) experience biventricular failure. Left ventricular assist devices (LVADs) are employed as a salvage therapy for individuals with advanced heart failure.
Qiuju Ding, Cheng Chen, Zhenjun Xu, Ning Zhang, Jun Pan, Min Ge   +5 more
doaj   +1 more source

Assessment of right ventricular function by echocardiography in patients with chronic heart failure

The Egyptian Heart Journal, 2018
Background: The main focus of most of the studies in heart failure (HF) is the assessment of the left ventricular functions, while the right ventricle was much less studied.
Viola William, Wael El Kilany
doaj   +1 more source