Advanced Science, EarlyView.This study presents decursin, a traditional Chinese medicine monomer, that inhibits lipid accumulation and inflammation in atherosclerosis through PKCδ interaction. A novel targeted delivery system (ALD@EM) is developed to overcome decursin's short half‐life, combining antibody‐mediated targeting, LDL‐facilitated chemotaxis, and enhanced macrophage ...
Hui Chen +13 more
wiley +1 more source
Autism Research, Volume 15, Issue 12, Page 2250-2264, December 2022., 2022 Abstract A growing body of research suggests that locus coeruleus‐norepinephrine (LC‐NE) system may function differently in individuals with autism spectrum disorder (ASD). Understanding the dynamics of both tonic (resting pupil diameter) and phasic (pupil dilation response [PDR] and event‐related potential [ERP]) indices may provide meaningful ...
Yesol Kim +3 more
wiley +1 more source
Physically motivated projection of the electrocardiogram -- a feasibility study [PDF]
We present PhysECG: a physically motivated projection of the 12 lead electrocardiogram, supported by a deep learning model trained on 21,799 recordings from the PTB-XL database and discuss its feasibility. The method allows to evaluate the epicardial activity (inverse problem of ECG imaging) and, in particular, to distinguish left and right ventricular
arxiv +1 more source
Advanced Science, EarlyView.The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du +21 more
wiley +1 more source
Global and regional right ventricular function in normal infants and infants with transposition of the great arteries after Senning operation. [PDF]
, 1985 E. Trowitzsch +2 more
openalex +1 more source
A Multi-Trait Approach Identified Genetic Variants Including a Rare Mutation in RGS3 with Impact on Abnormalities of Cardiac Structure/Function [PDF]
arXiv, 2018 Heart failure is a major cause for premature death. Given heterogeneity of the heart failure syndrome, identifying genetic determinants of cardiac function and structure may provide greater insights into heart failure. Despite progress in understanding the genetic basis of heart failure through genome wide association studies, heritability of heart ...
arxiv
Advanced Science, EarlyView.A unique hydrogel based on extracellular matrix from fish swim bladder, which is suitable for transcatheter delivery and possesses remarkable reparative capabilities for treating heart failure, is developed. It emerges as a multi‐effect factor profoundly influencing inflammation regulation, angiogenesis, and myocardial metabolism.
Yulong Fu +9 more
wiley +1 more source
RETRACTED: Influence of PEEP Ventilation Immediately after Cardiopulmonary Bypass on Right Ventricular Function [PDF]
, 1988 Joachim Boldt +4 more
openalex +1 more source
Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management
Advanced Science, EarlyView.Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang +4 more
wiley +1 more source
Extreme right ventricular hypoplasia after relief of severe pulmonary stenosis. Use of balloon catheter occlusion of atrial septal defect in assessing right ventricular function. [PDF]
, 1980 L. A. Cotter +2 more
openalex +1 more source