Results 181 to 190 of about 9,237,904 (297)

Dapagliflozin effects on right ventricular function, pulmonary pressure and coupling: a propensity score analysis from the RIVED-HF. [PDF]

ESC Heart Fail
Palazzuoli A, Ruocco G, Franceschi S, Schirò G, Petrini A, Manetti N, Salzano A, Severino P, Guazzi M, Crisci G, Barillà F, Mariano E, Dini FL, Di Santo M, Perrone Filardi P, Sorrentino G, Ghio S, Rosano GMC, Italian Heart Failure Study Group, Italian Society of Cardiology and the RIVED-HF investigators.   +19 more
europepmc   +1 more source

An Infusible Decellularized Extracellular Matrix Material Binds to Vasculature in Infarcted Myocardium and Induces Pro‐Reparative Gene Expression Following Acute Myocardial Infarction Through Inherent Avidity and Bioactive Signaling

Advanced Science, EarlyView.
To better characterize an infusible extracellular matrix (iECM) material, we applied size‐based fractionation to separate out components into two major fractions. We characterized these fractions to understand how material properties such as composition, morphology, and biochemical properties affect bioactive effects in the context of acute myocardial ...
Michael B. Nguyen, Alexander Chen, Quincy Lyons, Van K. Ninh, Maxwell C. McCabe, Colin Luo, Benjamin D. Bridgelal, Connor Uhre, Julian Cheng, Kate E. Reimold, Selena Cao, Kirk C. Hansen, Kevin R. King, Karen L. Christman   +13 more
wiley   +1 more source

Reproducibility of Echocardiographic Measurements of Right Ventricular Function: Comparison Between TAPSE and TDI S'. [PDF]

J Cardiovasc Dev Dis
Pagnoni G, Giuggioli D, Darroudi S, de Pinto M, Maini A, Spinella A, Sandri G, Pinti M, Aschieri D, Baccarani A, Mattioli AV, Fedele F, Coppi F.   +12 more
europepmc   +1 more source

Ischemic Postconditioning Protects Aged Myocardium Against Ischemia/Reperfusion Injury by Regulating Mitochondrial Dynamics via piR‐4913

Advanced Science, EarlyView.
A tiny RNA tips the scales of cardiac injury in aging. piR‐4913 recruits OGT to Drp1 and drives its O‐GlcNAcylation at Thr604, promoting excessive mitochondrial fission that aggravates ischemia‐reperfusion injury. Ischemic postconditioning silences this pathway to restore mitochondrial balance and protect the aged myocardium, revealing piR‐4913 as a ...
Xiangyu Zhao, Yanchun Li, Nan Li, Juan Zhang, Xiaolong Ma, Fei Yang, Ruihan Long, Yining Tian, Yichen Wang, Shengchao Ma, Huiping Zhang, Yideng Jiang   +11 more
wiley   +1 more source

Right Ventricular Function and Mortality in Critically Ill Patients With Heart Failure and Cardiogenic Shock. [PDF]

Int J Heart Fail
Lipps KM, Dahiya G, Jokhadar M, Bennett CE, Hillerson DB, Ternus BW, Crespo-Diaz RJ, Jentzer JC.   +7 more
europepmc   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source

17β-Estradiol counteracts pathological microtubule remodeling to enhance right ventricular function in preclinical models. [PDF]

J Clin Invest
Moon RA, Sobrano Fais R, Kim M, Vogel NT, Mendelson JB, Hartweck LM, Carney JP, Gardner MK, Prins SE, Prisco SZ, Lahm T, Prins KW.   +11 more
europepmc   +1 more source

A UBE3A‐UTX Proteostasis‐Epigenetic Axis Governs Hypothalamic Energy Homeostasis

Advanced Science, EarlyView.
Ubiquitin protein ligase E3A (UBE3A) regulates hypothalamic energy homeostasis and promotes degradation of the histone demethylase UTX (KDM6A). Neuronal UBE3A loss increases susceptibility to diet‐induced obesity and is accompanied by UTX accumulation, reduced histone H3 lysine 27 trimethylation, and altered endoplasmic reticulum stress‐responsive gene
Junekyoung Lee, Jaeyoung Yoo, Young A. Kim, Zhuodu Wei, Yunseo Lee, Woo‐Jeong Shon, Je Kyung Seong, Seunghee Lee   +7 more
wiley   +1 more source

Differential changes in longitudinal and area-based right ventricular function after aortic surgery: an exploratory echocardiographic study. [PDF]

BMC Surg
Akkaya BB, Sert DE, Yiğitbaşı MM, Gül EB, Yılmaz A, Akdi M, Karahan M, Mavioglu HL.   +7 more
europepmc   +1 more source

CD34+ Progenitors Promote Ageing‐Associated Valve Sclerosis through the PDGFR–JNK–JUNB Pathway

Advanced Science, EarlyView.
In age‐related aortic valve sclerosis, non‐bone marrow CD34+ progenitor valvular interstitial cells (VICs) undergo transdifferentiation into periostin+ myofibroblast‐like VICs via the PDGFR‐JNK‐JUNB axis, driving leaflet thickening and fibrosis. Ablating non‐bone marrow CD34+ cells attenuates this remodeling.
Xiaoping Yang, Hong Wu, Guoqiang Ren, Yuesheng Zhang, Zuoshi Wen, Pengwei Zhu, Zhangquan Ying, Liujun Jiang, Tingting Tao, Bohuan Zhang, Linwen Zhu, Han Wang, Han Zhang, Qingbo Xu, Jun Cheng, Honghua Ye   +15 more
wiley   +1 more source