Results 141 to 150 of about 2,531,746 (315)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Values, law and “discursive theory”: how the politicization of values triggers individualization in society

open access: yesGlocalism: Journal of Culture, Politics and Innovation, 2013
In this paper I want to claim that “politicization of values” will lead to individualization in society, in the long run, and further that this process will amount to a more personal form of legislation.
Mustafa Yaylali
doaj  

[Breakfast Festival for Human Rights Flyer]

open access: yes
Flyer advertising the Breakfast Festival for Human Rights in response to Anita Bryant's presence in Austin, Texas. The flyer states the festival is "A gathering of all the people of Austin who - by our presence - wish to affirm human rights and ...

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Rights, remedies & representation: a global report on access to justice for children

open access: yes, 2016
This report represents a snapshot of how the world has tried to develop mechanisms to protect children’s rights and ensure that there are remedies for violations of children’s rights. Summary Access to justice is a human right, but it is also what makes
Child Rights International Network
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

THE LAWYER'S PLEA [PDF]

open access: yesChallenges of the Knowledge Society
The science and art of speaking are essential in the practice of the profession of lawyer, and the persuasion of the plea depends on concise and precise expression, but also on the spontaneity and momentum of improvisation.
Andrada-Georgiana MARIN
doaj  

Other title: News; Other title: Title from OLRS publications screen : News from OLRS; Other title: Title from HTML version: News from Legal Rights Service; Other title: Title from HTML version: News from LRS; Other title: Title from HTML version: LRS newsletter

open access: yes, 2008
Aug. 2008; v. 1, issue 1 (Nov. 2008)-; Title varies.; "Ohio's Protection & Advocacy System for People with Disabilities."; Newsletter; information and updates about OLRS' case work and activities.; Harvested from the web on 7/10 ...
Ohio Legal Rights Service.
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