Results 51 to 60 of about 466,665 (308)
A Charter of Workers' Rights for Scotland [PDF]
1 Labour law as broadly defined is a reserved matter, though there has been a vigorous debate about its devolution by enhancing the powers of the Scottish Parliament. This is a debate that could continue for some time.
Ewing, Keith +4 more
core
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Rights-based reasoning in discussions about lesbian and gay issues: implications for moral educators [PDF]
Despite a paucity of psychological research exploring the interface between lesbian and gay issues and human rights, a human rights framework has been widely adopted in debates to gain equality for lesbians and gay men.
Ellis, S. J., Ellis, Sonia J.
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
In the formation of a new Constitution the constituents will require to know or reach an agreement on the nature of human rights; then, to determine how the State will enforce the respect to those rights.
Carlos López Dawson
doaj
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Discours écoféministes et droit de l'environnement : chassez le naturel ?
Ecofeminist thoughts have emerged during the seventies, aiming at highlighting the joint domination on feminine gender and nature. Yet, developping at the same time, modern environmental law does not seem to have been influenced by these ideas.
Romain Gosse
doaj +1 more source
Rights of Nature and the Antarctic: An Introduction
This publication provides an introduction to The Polar Journal's Special Issue on Rights of Nature and the Antarctic. The Special Issue aims to advance the scholarly discussion on Antarctic RoN. The authors discuss the concept of RoN and its relevance for the Antarctic, the interconnections between RoN and the recognition of Antarctica’s intrinsic ...
Yousra Makanse +2 more
openaire +2 more sources

