Results 81 to 90 of about 466,665 (308)

A Study of Student Perceptions on the Rights of Nature [PDF]

, 2023
This research article explores the concept of the Rights of Nature by reviewing survey results from undergraduate students at the University of North Carolina Wilmington (UNCW) on their perception of the Rights of Nature. The Rights of Nature are defined
NC DOCKS at The University of North Carolina Wilmington, Scudella, Jessica   +1 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Rights of Nature and the Lake Erie Bill of Rights

Open Rivers
By Sheryl Cunningham. On February 26, 2019, citizens of Toledo, Ohio, passed legislation called the Lake Erie Bill of Rights (LEBOR), which created legal standing for nature in the state of Ohio by giving individual citizens the right to sue on behalf of
Sheryl Cunningham
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

The Rights of Nature: Three Models

Sortuz
This article considers whether an approach to the rights of nature (RoN) that reproduces rights and legal personality (which we will call the Extension Model) can achieve the goal of profoundly transforming our relationship with nature. The paper argues,
Joel Colon Rios, Marina Lostal
doaj   +1 more source

Exploring contestation in rights of river approaches: Comparing Colombia, India and New Zealand

Water Alternatives, 2022
Rights of Nature (RoN) approaches as a tool to protect ecosystems and nature is gaining growing attention in academic and societal debates. Despite this new momentum, theoretical work is increasingly pointing out major problems and uncertainties ...
Marco Immovilli, Susanne Reitsma, Regine Roncucci, Elisabet Dueholm Rasch, Dik Roth   +4 more
doaj  

Children's Green Infrastructure: Children and Their Rights to Nature and the City. [PDF]

Front Sociol, 2022
Vidal DG, Castro Seixas E.
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Private Rights of Nature

, 2022
The Rights of Nature concept not only breaks with the anthropocentrism of existing (environmental) law; it also recognizes that nature has private interests, in addition to being of public interest.
Burgers, L.
core   +1 more source