Results 101 to 110 of about 3,322,138 (297)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Why is a European Law on Disability Discrimination important [PDF]

open access: yes, 2001
EU law offers great potential for advancing the rights and interests of disabled people living within the European Union, but this potential is yet to be fully realised.
Whittle, R.
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Contemplative Life amidst Mass Extinction: Catholic Revisions of Spirituality, Law, and Multispecies Justice

open access: yesJournal of Contemplative Studies
Contemplative ecologies seem to face two liabilities of injustice. First, they may appear to seek spiritual satisfaction in multispecies relations without connection to political work to protect them from extinction.
Willis Jenkins
doaj   +1 more source

Sustainable hunting tourism - business opportunity in Northern areas? Overview of hunting and hunting tourism in four Northern countries: Finland, Sweden, Iceland and Canada [PDF]

open access: yes, 2007
The social sustainability and fluent co-operation with the interest groups is perhaps the most crucial issue related to the development of hunting tourism at the moment.
Anne, Matilainen (ed.)
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

International Rights of Nature

open access: yes, 2023
Völkerrechtsblog
openaire   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Rights and relationality: A review of the role of law in the human/water relationship

open access: yesWater Alternatives
In this review, we use legal scholarship to explore the way that the law constructs and maintains discourses on both water rights and water relationality.
Erin O’Donnell   +2 more
doaj  

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