Results 131 to 140 of about 1,606,068 (311)

Incorporating the voice of the child into clinical assessments for children in need

open access: yesChild Protection and Practice
Background: Upholding the voice of the child (VOC) in clinical encounters is critical to realising their rights. Evidence from inquiry reports however demonstrate that practitioners fail to adequately listen to the voice of the child in the child ...
Katie Newman, Shanti Raman, Allison Ward
doaj   +1 more source

A child's right to health [PDF]

open access: yesThe Lancet, 2019
Stefan, Peterson   +4 more
openaire   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Adoption by Lesbian and Gay People: The Use and Mis-Use of Social Science Research [PDF]

open access: yes, 1995
In the past twenty years, openly lesbian and gay people have joined in the evolving national dialogue, within the law and elsewhere, about adoption.
Elovitz, Marc E.
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Ósýnileiki barna sem leita alþjóðlegrar verndar á Íslandi í fylgd foreldra

open access: yesNordicum-Mediterraneum, 2019
Invisibility of children of asylum-seeking families in Iceland According to the Convention on the Rights of the Child, asylum-seeking children should be given the same rights as other children in Iceland.
Helga Gudmundsdóttir   +2 more
doaj  

Book review: Abrams, L.S. and Anderson-Nathe, B. (2013). Compassionate confinement: A year in the life of unit C. New Jersey: Rutgers University Press. 188pp., ISBN 978-0-8135-5412-9

open access: yesScottish Journal of Residential Child Care, 2015
I have to admit that I approached this review with some prejudices. When working at the University of Strathclyde, I took part in the Social Work Department's long-standing exchange with the University of North Carolina at Greensboro.
Mark Smith
doaj   +1 more source

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