Results 111 to 120 of about 1,606,068 (311)

Educația și respectarea dreptului la educație în România [PDF]

open access: yesDrepturile Omului, 2019
his paper analyses the topic of Education and the right to education in Romania from the perspective of the principles and provisions of the Convention on the Rights of the Child. The study is comprised of two sections: the first part consists of a brief
Anca Moț
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

ANALISIS PENEMPATAN TERSANGKA ANAK BERSAMA DENGAN ORANG DEWASA DALAM PERSPEKTIF PERLINDUNGAN HUKUM ANAK DI KEPOLISIAN RESORT PASER KALIMANTAN TIMUR [PDF]

open access: yes
The investigation process is an initial stage where a child is confronted by investigators or the police. The child suspect was placed in the same cell as the adult prisoner. This is clearly contrary to Law Number 11 of 2012 concerning the Child Criminal
Aprillianti, Riska
core  

Developing the Substantive Best Interests of Child Migrants: A Call for Action [PDF]

open access: yes, 2012
This Article attempts to accomplish two goals. First, it provides an overview of what is known and unknown about international child migrants. While this Conference will focus to some degree on child migrants in the United States, this Article shows how ...
Schoenholtz, Andrew I.
core   +3 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The right to live in a family and the subsidiarity of adoption in the light of the best interests of the childs

open access: yesRevista Facultad de Jurisprudencia, 2019
Adoption rates in Chile, in relation to the number of children placed in alternative care systems, are considerably low. Although there are a multiplicity of factors that motivate the previous situation, one that we consider of particular relevance, is ...
Alejandra Illanes Valdés
doaj  

Law, Property, and Marital Dissolution [PDF]

open access: yes
This paper challenges the view that legal rights are not important in affecting whether people divorce, but it puts as much emphasis on property rights (given, for example, by the law on alimony) as on dissolution rights.
Simon Clark
core  

What’s Wrong With Victims’ Rights in Juvenile Court?: Retributive v. Rehabilitative Systems of Justice [PDF]

open access: yes, 2009
While scholars have written extensively about the victims’ rights movement in capital and criminal cases, there has been very little discussion about the intersection of victims’ rights and the juvenile justice system.
Henning, Kristin N.
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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