Results 91 to 100 of about 186,715 (265)

Editorial: Sleep, vigilance & disruptive behaviors

Frontiers in Psychiatry, 2023
Osman S. Ipsiroglu, Gerhard Klösch, Rosalia Cesarea Silvestri, Susan Mary McCabe, Georg Dorffner, Thomas Christian Wetter, Luci Wiggs   +6 more
doaj   +1 more source

A child's right to health [PDF]

The Lancet, 2019
Stefan, Peterson, Luwei, Pearson, Robin, Nandy, Debra, Jackson, David, Hipgrave   +4 more
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Work of the Council of Europe Parliamentary Assembly and Relevant Case-Law of the European Court of Human Rights Concerning Intercountry Adoption [PDF]

Societas et Iurisprudentia, 2015
The paper points out particularly to the Resolution of the Parliamentary Assembly of the Council of Europe No. 1909 (2012) on Intercountry Adoption: Ensuring that the Best Interests of the Child Are Upheld, emphasising the necessity to prevent and to ...
Eva Vančová
doaj  

Did the UN convention on the rights of the child reduce child mortality around the world? An interrupted time series analysis. [PDF]

BMC Public Health, 2020
Tait CA, Parnia A, Zewge-Abubaker N, Wong WH, Smith-Cannoy H, Siddiqi A.   +5 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Les associations des enfants et jeunes travailleurs du Burkina Faso comme espace d’expression de la capacité d’action des enfants ?

Enfances, Familles, Générations, 2016
Since the adoption of the United Nations Convention on the Rights of the Child in 1989, taking into account the children’s point of view on decisions that affect them (article 12 of the Convention) has become increasingly popular.
Joséphine Wouango
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Incorporating the voice of the child into clinical assessments for children in need

Child Protection and Practice
Background: Upholding the voice of the child (VOC) in clinical encounters is critical to realising their rights. Evidence from inquiry reports however demonstrate that practitioners fail to adequately listen to the voice of the child in the child ...
Katie Newman, Shanti Raman, Allison Ward
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source