The Age at Onset of LRRK2 p.Gly2019Ser Parkinson's Disease Across Ancestries and Countries of Origin
Objectives The objective of this study was to elucidate differences in the cumulative incidence of Leucine‐rich repeat kinase 2 (LRRK2) p.Gly2019Ser‐related Parkinson's disease (PD; LRRK2‐PD) between ancestries and countries. Methods We included 922 unrelated p.Gly2019Ser variant carriers (affected = 762 and unaffected = 160) from the Global Parkinson ...
Theresa Lüth +14 more
wiley +1 more source
Temporoparietal Fascial Free Flap With Vascularized Helical Rim Component for Complex Nasal Reconstruction. [PDF]
Nanda AD +4 more
europepmc +1 more source
The role of microglia has emerged as a critical driver of disease progression in multiple sclerosis (MS), but we lack broadly applicable monitoring tools. Here, we investigated whether hyperreflective foci (HRF), as detected by optical coherence tomography (OCT) within the inner nuclear layer (INL) of the retina, can be used as a marker for microglial ...
Jonathan A. Gernert +13 more
wiley +1 more source
Magnesium- and biopolymer-stabilized ACC and ACP form the body-wall spicules of Baptodoris cinnabarina (Doridida, Gastropoda). [PDF]
Griesshaber E +10 more
europepmc +1 more source
Amphibole reaction rims record shear during magma ascent. [PDF]
Wallace PA +9 more
europepmc +1 more source
Focal intratesticular lesions including spontaneous hematomas in the acute scrotum: the pivotal role of ultrasound and MRI in diagnosis and management-a pictorial review. [PDF]
Rocher L +6 more
europepmc +1 more source
Mechanistic Basis of Cholesterol Binding and Transfer in NPC2: Insights From Molecular Dynamics Simulations. [PDF]
Patel S, Elghobashi-Meinhardt N.
europepmc +1 more source
Two-dimensional transthoracic echocardiography versus two-dimensional trans esophageal echocardiography for assessment of moderate to large atrial septal defects and the device size in pediatric patients before transcatheter closure. [PDF]
Adel HM +3 more
europepmc +1 more source

