Results 211 to 220 of about 1,628,729 (281)

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Flow synthesis of polysubstituted pyrroles <i>via</i> a Vilsmeier-chloroacrolein strategy. [PDF]

RSC Adv
Dwomoh K, Ramirez E, Minami F, Mandry CP, Kim A, Chandler E, West J, Fisher D, Dominey RN, Goldman EW.   +9 more
europepmc   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

C1-ring osteosynthesis for Jefferson fracture: a multi-institutional retrospective case series. [PDF]

J Trauma Inj
Park H, Kim W, Sim J, Myeong HS, Lee S, Kim JH, Lee CH, Tsuang FY, Kim CH.   +8 more
europepmc   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Functional analysis of the methanobactin-encoding gene cluster of <i>Methylocystis</i> sp. strain SB2. [PDF]

Microbiol Spectr
Peng P, Bobik T, DiSpirito AA, Semrau JD.   +3 more
europepmc   +1 more source

Macular Thickness and Associated Factors in African Immigrants: Insights from the Africans in America Study. [PDF]

Clin Ophthalmol
Prasad M, Agrón E, Arunachalam T, Mukherjee S, Siddig F, Duic C, Thavikulwat AT, Keenan TDL, Cukras C, Smith GG, DuBose CW, Chew EY, Sumner AE.   +12 more
europepmc   +1 more source