Results 251 to 260 of about 1,393,313 (319)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Ring Artifact Reduction in Photon Counting CT Using Redundant Sampling and Autocalibration. [PDF]

IEEE Trans Med Imaging
Hsieh SS, Day J, Deng X, Bazalova-Carter M.   +3 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Hepatic pseudolymphoma with hepatobiliary-phase ring-like hyperintensity on gadoxetic acid-enhanced MRI: radiologic-pathologic correlation with intratumoral fibrosis. [PDF]

BJR Case Rep
Nagata S, Fujimoto N, Tonan T, Chikasue T, Sumi A, Akiba J, Tanoue S.   +6 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Preparation of 3-(alkylamino)imidazo[1,2-<i>a</i>]pyridine-2-carbaldehydes via Kornblum oxidation and unexpected ring-opening reactions of the corresponding alcohols under oxidative conditions. [PDF]

Beilstein J Org Chem
Mkhize SJ, Zimuwandeyi M, Fernandes MA, Rousseau AL, Bode ML.   +4 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Patients with an acetabular fracture treated with acute total hip arthroplasty and additional fixation: a cohort study with functional and radiological follow-ups. [PDF]

Acta Orthop
Chang D, Koskinen SK, Enocson A.
europepmc   +1 more source

The Ringed World: Saturn from Cassini to The James Webb Space Telescope. [PDF]

Nat Commun
Tiranti P.
europepmc   +1 more source

Design and Development of Sectional-Chain Silicon Drift Detectors with Diversity Elliptical-Shaped Voltage Dividers. [PDF]

Micromachines (Basel)
Ni C, Long T, Zhao J, Song X, Li X, Liu M, Liu Z, Zhu X, Li Z.   +8 more
europepmc   +1 more source