Results 151 to 160 of about 3,716,677 (247)

Investigation of Sulfur-related Influences on the Construction and Ring Opening of a Six-membered Cyclic Xanthate Derived from d-Thymidine and CS2. [PDF]

J Am Chem Soc
Andras AM, Fatima N, Kuo KM, Tran DK, Darensbourg DJ, Wooley KL.   +5 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Discovery of tricyclic benzo[4,5]imidazo[2,1-<i>b</i>]thiazole-3-hydroxyindolin-2-one hybrids as selective MAO-B and cholinesterase inhibitors. [PDF]

RSC Adv
Eldehna WM, El-Damasy AK, Lim J, Hewala MM, Elsayed ZM, Al-Warhi T, El-Hamaky AA, Paik MJ, Keum G, Elnagar MR, Kim H, Tawfik HO.   +11 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Leveraging Cubenes to Access Highly Functionalized Fused Cubes. [PDF]

J Am Chem Soc
French SA, Rivera CA, Chung KK, Houk KN, Garg NK.   +4 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

PhD Chemistry Community Christmas Symposium Basel 2025

CHIMIA
Elias Behling, Pieter Brongers, Chiara Disraeli, Ilse Friedländer, Nils Gerwien, Salome Heim, Richard Karl, Ana-Maria Juric, Livia Müller, Andreas Ostertag, Minqi Pan, Shimoni Patel, Anies Rösch, Stephan Schumann, Malte Sellin, Luise Sokoliuk, Anne Stoppel, Joël Wellauer , Amine Yücekul   +18 more
doaj   +1 more source

Recent advancements in visible light-induced, vitamin-catalysed chemical transformations. [PDF]

RSC Adv
Tivari S, Kumar Jaiswal S, Yadav B, Pandey A, Kumar R, Singh PK, Singh PP, Srivastava V.   +7 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source