Results 11 to 20 of about 49,972 (158)

5,6-Dihydro-[1,2,5]oxadiazolo[3,4-d]pyridazine-4,7-dione

open access: yesMolbank, 2023
1,2,5-Chalcogenadiazoles fused with electron-withdrawing heterocycles have been actively investigated for the preparation of organic photovoltaic materials. [1,2,5]Oxadiazolo[3,4-d]pyridazines are much less studied than other chalcogenadiazolopyridazines
Timofey N. Chmovzh   +2 more
doaj   +1 more source

N-[3-(Chloromethyl)-1,2-benzisoxazol-5-yl]acetamide

open access: yesMolbank, 2022
Functionally substituted 1,2-benzisoxazoles are very important and promising heterocycles with various pharmacological activities. Benzoxazoles containing reactive 3-chloromethyl and 5-amino groups are practically unexplored derivatives in this series ...
Evgeniy N. Khodot, Oleg A. Rakitin
doaj   +1 more source

6-Endo-dig cyclization: Flexible enforce to develop synthetic route in organic syntheses

open access: yesResults in Chemistry, 2023
The organic ring closure reaction of diverse acyclic compounds is governed mostly by the Baldwin rule. The ring closure compounds shows emergent application.
Vembu Yogeshwaran   +3 more
doaj   +1 more source

Synthesis of Fully Functionalized 3-Bromoazaspiro[4.5]trienones through Ugi Four-Component Reaction (Ugi-4CR) followed by ipso-Bromocyclization

open access: yesSynOpen, 2018
Biologically attractive azaspiro[4.5]trienones have been prepared via Ugi four-component reaction (Ugi-4CR) followed by bromine-mediated ipso-cyclization.
Saeed Balalaie   +5 more
doaj   +1 more source

Cytokinetic diversity in mammalian cells is revealed by the characterization of endogenous anillin, Ect2 and RhoA

open access: yesOpen Biology, 2022
Cytokinesis is required to physically separate the daughter cells at the end of mitosis. This crucial process requires the assembly and ingression of an actomyosin ring, which must occur with high fidelity to avoid aneuploidy and cell fate changes.
Mathieu C. Husser   +4 more
doaj   +1 more source

Novel stereocontrolled syntheses of tashiromine and epitashiromine

open access: yesBeilstein Journal of Organic Chemistry, 2015
A novel stereocontrolled approach has been developed for the syntheses of tashiromine and epitashiromine alkaloids from cyclooctene β-amino acids. The synthetic concept is based on the azetidinone opening of a bicyclic β-lactam, followed by oxidative ...
Loránd Kiss   +2 more
doaj   +1 more source

A New Approach to the Total Synthesıs of (±)-Nordasycarpıdone by Rıng-closure wıth Tetrachloro-1,4-benzoquınone

open access: yesMacedonian Journal of Chemistry and Chemical Engineering, 2020
A new synthetic route for the  (±)-nordasycarpidone was achieved in five steps with an overall yield of  41%. This route involves  ring closure and formation of 5 which has a  methanoazocino[4,3-b]indole skeleton in the key step.
Nesimi Uludag
doaj   +1 more source

Preparation of Substituted Methyl o-Nitrophenyl Sulfides

open access: yesMolecules, 2002
The nucleophilic substitution of substituted o-nitrochlorobenzenes with substituted methanethiolates, catalysed with triethylamine or pyridine, has been used to prepare a series of appropriately substituted methyl-o-nitrophenylsulfides.
Petr Simunek   +3 more
doaj   +1 more source

Towards stereochemical control: A short formal enantioselective total synthesis of pumiliotoxins 251D and 237A

open access: yesBeilstein Journal of Organic Chemistry, 2013
A concise enantioselective synthesis of the advanced intermediate 5 for the synthesis of pumiliotoxins (Gallagher’s intermediate) is described. The synthesis started from the regio- and trans-diastereoselective (dr = 98:2) reductive 3-butenylation of (R)-
Jie Zhang   +2 more
doaj   +1 more source

ILM Flap Repositioning for Persistent Macular Hole

open access: yesCase Reports in Ophthalmology, 2022
We present a case of a persistent macular hole which was initially treated by pars plana vitrectomy with the inverted ILM flap technique. In a second procedure, the internal limiting membrane (ILM) flap was mobilized from its perifoveal adherence to the ...
Gregor Kastl, Peter Heidenkummer
doaj   +1 more source

Home - About - Disclaimer - Privacy