Results 11 to 20 of about 49,972 (158)
5,6-Dihydro-[1,2,5]oxadiazolo[3,4-d]pyridazine-4,7-dione
1,2,5-Chalcogenadiazoles fused with electron-withdrawing heterocycles have been actively investigated for the preparation of organic photovoltaic materials. [1,2,5]Oxadiazolo[3,4-d]pyridazines are much less studied than other chalcogenadiazolopyridazines
Timofey N. Chmovzh +2 more
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N-[3-(Chloromethyl)-1,2-benzisoxazol-5-yl]acetamide
Functionally substituted 1,2-benzisoxazoles are very important and promising heterocycles with various pharmacological activities. Benzoxazoles containing reactive 3-chloromethyl and 5-amino groups are practically unexplored derivatives in this series ...
Evgeniy N. Khodot, Oleg A. Rakitin
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6-Endo-dig cyclization: Flexible enforce to develop synthetic route in organic syntheses
The organic ring closure reaction of diverse acyclic compounds is governed mostly by the Baldwin rule. The ring closure compounds shows emergent application.
Vembu Yogeshwaran +3 more
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Biologically attractive azaspiro[4.5]trienones have been prepared via Ugi four-component reaction (Ugi-4CR) followed by bromine-mediated ipso-cyclization.
Saeed Balalaie +5 more
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Cytokinesis is required to physically separate the daughter cells at the end of mitosis. This crucial process requires the assembly and ingression of an actomyosin ring, which must occur with high fidelity to avoid aneuploidy and cell fate changes.
Mathieu C. Husser +4 more
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Novel stereocontrolled syntheses of tashiromine and epitashiromine
A novel stereocontrolled approach has been developed for the syntheses of tashiromine and epitashiromine alkaloids from cyclooctene β-amino acids. The synthetic concept is based on the azetidinone opening of a bicyclic β-lactam, followed by oxidative ...
Loránd Kiss +2 more
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A new synthetic route for the (±)-nordasycarpidone was achieved in five steps with an overall yield of 41%. This route involves ring closure and formation of 5 which has a methanoazocino[4,3-b]indole skeleton in the key step.
Nesimi Uludag
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Preparation of Substituted Methyl o-Nitrophenyl Sulfides
The nucleophilic substitution of substituted o-nitrochlorobenzenes with substituted methanethiolates, catalysed with triethylamine or pyridine, has been used to prepare a series of appropriately substituted methyl-o-nitrophenylsulfides.
Petr Simunek +3 more
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A concise enantioselective synthesis of the advanced intermediate 5 for the synthesis of pumiliotoxins (Gallagher’s intermediate) is described. The synthesis started from the regio- and trans-diastereoselective (dr = 98:2) reductive 3-butenylation of (R)-
Jie Zhang +2 more
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ILM Flap Repositioning for Persistent Macular Hole
We present a case of a persistent macular hole which was initially treated by pars plana vitrectomy with the inverted ILM flap technique. In a second procedure, the internal limiting membrane (ILM) flap was mobilized from its perifoveal adherence to the ...
Gregor Kastl, Peter Heidenkummer
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