Results 141 to 150 of about 12,413,187 (395)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

A Comparative Study of the Differential Deep Penetration of Energetic Electrons, Protons, and Heavy Ions Into the Low‐L Region

Geophysical Research Letters
Energetic particle deep penetration into low L‐shells (L 
Rui Chen, Hong Zhao, Sam Califf, Cristian Ferradas, Mei‐Ching Fok   +4 more
doaj   +1 more source

Statistical Properties of Molecular Ions in the Ring Current Observed by the Arase (ERG) Satellite

Geophysical Research Letters, 2019
Molecular ions in the magnetosphere can be a tracer of fast ion outflows from the deep ionosphere. Statistical properties of molecular ions (O2+/NO+/N2+) in the ring current are investigated based on ion composition measurements (
K. Seki, K. Keika, S. Kasahara, S. Yokota, T. Hori, K. Asamura, N. Higashio, M. Takada, Y. Ogawa, A. Matsuoka, M. Teramoto, Y. Miyoshi, I. Shinohara   +12 more
doaj   +1 more source

Coherent ring-current migration of Mg-phthalocyanine probed by time-resolved X-ray circular dichroism. [PDF]

Chem Sci, 2022
Sun S, Yong H, Chen F, Mukamel S.
europepmc   +1 more source

Decoherence from Vacuum Fluctuations

, 2001
Vacuum fluctuations are a source of irreversibility and decoherence. We investigate the persistent current and its fluctuations in a ring with an in-line quantum dot with an Aharonov-Bohm flux through the hole of the ring.
Buttiker, Markus
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Superconducting fluctuation current in a space with the Kerr metric

, 2019
We study a fluctuation current through a superconducting ring placed in a space with the Kerr metric. This attempt aims at exploring conceptual problem; namely, we are concerned with the question about the condensed state in an extreme space-time.
Kuratsuji, Hiroshi, Tsuchida, Satoshi
core   +1 more source

Influence of ionosphere conductivity on the ring current [PDF]

, 2004
Yusuke Ebihara, Mei‐Ching Fok, R. A. Wolf, T. J. Immel, T. E. Moore   +4 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Identification of ring current proton precipitation driven by scattering of electromagnetic ion cyclotron waves. [PDF]

Fundam Res, 2023
Ni B, Zhang Y, Gu X.
europepmc   +1 more source