Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Equivariant Quantum Schubert Polynomials [PDF]
We establish an equivariant quantum Giambelli formula for partial flag varieties. The answer is given in terms of a specialization of universal double Schubert polynomials.
Anderson, D., Chen, Linda
core +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Irreducible Jacobian derivations in positive characteristic
We prove that an irreducible polynomial derivation in positive characteristic is a Jacobian derivation if and only if there exists an n-1-element p-basis of its ring of constants. In the case of two variables we characterize these derivations in terms of
Jedrzejewicz, Piotr
core +2 more sources
A user-friendly Matlab program and GUI for the pseudorotation analysis of saturated five-membered ring systems based on scalar coupling constants [PDF]
Background: The advent of combinatorial chemistry has revived the interest in five-membered heterocyclic rings as scaffolds in pharmaceutical research. They are also the target of modifications in nucleic acid chemistry.
Hendrickx, Pieter, Martins, José
core +4 more sources
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Simultaneous $p$-orderings and minimising volumes in number fields
In the paper "On the interpolation of integer-valued polynomials" (Journal of Number Theory 133 (2013), pp. 4224--4232.) V. Volkov and F. Petrov consider the problem of existence of the so-called $n$-universal sets (related to simultaneous $p$-orderings ...
Byszewski, Jakub +2 more
core +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
On the Structure of the Small Quantum Cohomology Rings of Projective Hypersurfaces
We give an explicit procedure which computes for degree $d \leq 3$ the correlation functions of topological sigma model (A-model) on a projective Fano hypersurface $X$ as homogeneous polynomials of degree $d$ in the correlation functions of degree 1 ...
Collino, A., Jinzenji, M.
core +1 more source

