Results 91 to 100 of about 1,345,046 (291)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Unobtrusive stress detection using wearables: application and challenges in a university setting
IntroductionIn theory, wearable physiological sensing devices offer an opportunity for institutions to monitor and manage the health and well-being of a group of people.
Peter Neigel +3 more
doaj +1 more source
On Zero-Symmetric Left Centrally Prime Near-Rings [PDF]
Our aim in this paper is: to give some properties of zero-symmetric left centrally prime near-rings, then looking for those conditions which make zero-symmetric left centrally prime near-rings abelian, so that several conditions are given under which ...
doaj +1 more source
Integrable N = 2 Landau-Ginzburg Theories from Quotients of Fusion Rings
The discovery of integrable $N=2$ supersymmetric Landau-Ginzburg theories whose chiral rings are fusion rings suggests a close connection between fusion rings, the related Landau-Ginzburg superpotentials, and $N=2$ quantum integrability.
Aharony +54 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A Manuscript Description in Kraków of the ‘Trivulzio Museum’ in Milan
An early nineteenth-century manuscript is preserved in the Jagiellonian Library in Kraków. This document in Italian, entitled ‘Breve Descrizione del Museo Trivulzio’, describes the contents of a collection of an aristocratic family in Milan, as seen ...
Hadrien J. Rambach
doaj +1 more source
Armendariz Rings and Reduced Rings
According to \textit{D. D. Anderson} and \textit{V. Camillo} [Commun. Algebra 26, No. 7, 2265-2272 (1998; Zbl 0915.13001)], a ring \(R\) is called Armendariz if whenever polynomials \(f(x)=a_0+a_1x+\cdots+a_m x^m\) and \(g(x)=b_0+b_1x+\cdots+b_nx^n\) in \(R[x]\) satisfy \(f(x)g(x)=0\), then \(a_ib_j=0\) for each \(i\), \(j\). It is shown that if a ring
Kim, Nam Kyun, Lee, Yang
openaire +2 more sources

