The diabetes-associated K<sup>+</sup> channel TALK-2 controls human beta cell endoplasmic reticulum Ca<sup>2+</sup> handling, which promotes basal insulin release and limits glucose-stimulated insulin secretion. [PDF]
Dobson JR +9 more
europepmc +1 more source
The Geography of Success: A Spatial Analysis of Export Intensity in the Italian Wine Industry
ABSTRACT This paper investigates the paradox of how Italy's fragmented, SME‐dominated wine industry achieves global export success. Moving beyond purely firm‐centric explanations, we test whether export intensity is spatially dependent, clustering geographically in regional ecosystems.
Nicolas Depetris Chauvin, Jonas Di Vita
wiley +1 more source
New focus on cardiac voltage-gated sodium channel β1 and β1B: Novel targets for treating and understanding arrhythmias? [PDF]
Williams ZJ, Payne LB, Wu X, Gourdie RG.
europepmc +1 more source
ABSTRACT In the agricultural landscape of most developing countries, the last decade has witnessed the expansion of outsourced agricultural extension services. Private firms and nongovernmental organizations focused on delivering agricultural extension and advisory services to farmers have emerged.
Boris D. Soh Wenda +3 more
wiley +1 more source
Dimorphic neural network architecture prioritizes sexual-related behaviors in male <i>Caenorhabditis elegans</i>. [PDF]
Wang X +14 more
europepmc +1 more source
Deforestation and Efficiency: Insights From Forest Transition in the Brazilian Cerrado
ABSTRACT This paper estimates technical efficiency (TE) and environmental efficiency (EE) of agricultural production at the municipal level of the Brazilian Cerrado in 2006 and 2017, and investigates their underlying mechanisms in relation to forest transition theory.
Ricardo Muniz Simões +2 more
wiley +1 more source
Epidemiological and clinical characteristics of seawater drowning cases in Sinop, a Turkish coastal city: a 13-year retrospective study. [PDF]
Erşen T +7 more
europepmc +1 more source
Automated generative process synthesis via transformer‐based dual‐loop simulation and optimization
Abstract This study presents a novel framework for automated generative process synthesis, addressing the complexity of simultaneously optimizing discrete topologies and continuous operating variables. To overcome conventional superstructure limitations, we propose a dual‐loop architecture integrating generative transformers with rigorous process ...
Yeong Woo Son +4 more
wiley +1 more source
The m6A Demethylase Fto Enhances Susceptibility to Atrial Fibrillation by Demethylating Kcne1 in Aging Mice. [PDF]
Tan R +8 more
europepmc +1 more source
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz +2 more
wiley +1 more source

