Results 101 to 110 of about 893,386 (319)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

CRISPR/cas9 Allows for the Quick Improvement of Tomato Firmness Breeding

Current Issues in Molecular Biology
Fruit firmness is crucial for storability, making cultivating varieties with higher firmness a key target in tomato breeding. In recent years, tomato varieties primarily rely on hybridizing ripening mutants to produce F1 hybrids to enhance firmness ...
Qihong Yang, Liangyu Cai, Mila Wang, Guiyun Gan, Weiliu Li, Wenjia Li, Yaqin Jiang, Qi Yuan, Chunchun Qin, Chuying Yu, Yikui Wang   +10 more
doaj   +1 more source

A Clathrin-Related Protein, SCD2/RRP1, Participates in Abscisic Acid Signaling in Arabidopsis

Frontiers in Plant Science, 2020
Abscisic acid (ABA) plays important roles in many aspects of plant growth and development, and responses to diverse stresses. Although much progress has been made in understanding the molecular mechanisms of ABA homoeostasis and signaling, the mechanism ...
Bingzhu Hou, Bingzhu Hou, Yuanyue Shen
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Arabidopsis thaliana DOF6 negatively affects germination in non-after ripened seeds and interacts with TCP14 [PDF]

, 2011
Seed dormancy prevents seeds from germinating under environmental conditions unfavourable for plant growth and development and constitutes an evolutionary advantage.
Barrero Sicilia, Cristina, Gomez Cadenas, Aurelio, Oñate Sanchez, Luis, Carbonero Zalduegui, Pilar, Rueda Romero, Paloma   +4 more
core   +1 more source

Spark to blaze: the role of ethylene in achenes and the ripple influences on strawberry fruit growth and ripening

Fruit Research
Strawberry, considered to be a model for non-climacteric fruits, has traditionally been viewed as having a less pronounced reliance on ethylene in fruit development.
Huixin Chen, Dongdong Li, Kunsong Chen
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Proteomic Analysis of Chloroplast-to-Chromoplast Transition in Tomato Reveals Metabolic Shifts Coupled with Disrupted Thylakoid Biogenesis Machinery and Elevated Energy-Production Components [PDF]

, 2012
A comparative proteomic approach was performed to identify differentially expressed proteins in plastids at three stages of tomato(Solanum lycopersicum) fruit ripening (mature-green, breaker, red). Stringent curation and processing of the data from three
Bouyssie, David, Bian, Wanping, Barsan, Cristina, Rossignol, Michel, Bouzayen, Mondher, Picheraux, Carole, Latché, Alain, Egea Sanchez, Isabel, Pech, Jean-Claude, Pichereaux, Carole, Maza, Elie, Egea, Isabel, Zouine, Mohamed, Zouine, Mohammed, Purgatto, Eduardo   +14 more
core   +1 more source

[PROVISIONAL] Molecular characterization and transcription analysis of DNA methyltransferase genes in tomato (Solanum lycopersicum)

Genetics and Molecular Biology
DNA methylation plays an important role in plant growth and development, gene expression regulation and maintenance of genome stability. However, only little information regarding development- or stress-related DNA methyltransferases (MTases) genes is ...
Xuhu Guo, Qian Xie, Baoyuan Li, Huanzhen Su   +3 more
doaj   +1 more source