Results 51 to 60 of about 183,779 (306)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Dynamic Analysis of a Boost Topology with Ripple Cancellation and Comparison with the Conventional Boost [PDF]

open access: yes, 2009
The boost topology with ripple cancellation network allows input and output current ripple attenuation, which means the suppression of the input filter and a high reduction of the output filter. However, to achieve the ripple cancellation, the complexity
Alou Cervera, Pedro   +5 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Torque ripple suppression in non‐commutation interval of the coreless brushless DC motor based on unipolar PWM predictive control

open access: yesIET Power Electronics
Aiming at the torque ripple caused by significant current ripple and non‐ideal back‐electromotive force (back‐EMF) of coreless brushless DC motor (BLDCM), an incremental predictive control strategy based on unipolar pulse width modulation (PWM) is ...
Chong Zeng   +3 more
doaj   +1 more source

Ripple cancellation technique applied to a synchronous buck converter to achieve very high bandwidth and very high efficiency envelope amplifier [PDF]

open access: yes, 2013
This work presents a single stage converter for a high bandwidth and a high efficiency envelope amplifier. The current ripple cancellation technique is applied to a synchronous buck converter to cancel the output current ripple and to decrease the ...
Alou Cervera, Pedro   +4 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Research on Calculation Method of DC Side Capacitor Ripple Components for Three-level Inverter

open access: yesKongzhi Yu Xinxi Jishu, 2020
Ripple current of DC side capacitor affects capacity selection and life of a capacitor, and ripple voltage of capacitor affects the voltage that power device needs to bear, so analysis of capacitor ripple components is very important for the design of ...
ZHANG Honghao   +4 more
doaj  

Floating Interleaved Boost Converter with Zero-Ripple Input Current Using Variable Inductor

open access: yesTechnologies, 2023
A zero-ripple input current is known to improve the lifetime of battery sets and fuel cells and to assure maximum power point tracking in PV panels.
Hector Hidalgo   +5 more
doaj   +1 more source

Self-stabilized Nonlinear Lateral Modes of Broad Area Lasers [PDF]

open access: yes, 1987
The lateral modes of broad area lasers are investigated theoretically. The nonlinear interaction between optical field and effective refractive index leads to a saturable nonlinearity in the governing field equation, so that self-modulated solutions are ...
Lang, Robert J.   +4 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

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