ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Assessment of torque components in brushless permanent-magnet machines through numerical analysis of the electromagnetic field [PDF]
For the calculation of torque in brushless (BL) alternating current motors a local method is proposed, based on the Maxwell stress theory and the filtered contributions due to the harmonics of the magnetic vector potential in the motor air gap.
Dellinger, S.J. +4 more
core +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Steady-state analysis and modelling of power factor correctors with appreciable voltage ripple in the output-voltage feedback loop to achieve fast transient response [PDF]
The classical design of an active power factor corrector (PFC) leads to slow transient response in this type of converter. This is due to the fact that the compensator placed in the output-voltage feedback loop is usually designed to have narrow ...
Fernández González, Arturo José +4 more
core +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Direct torque control of brushless DC drives with reduced torque ripple [PDF]
The application of direct torque control (DTC) to brushless ac drives has been investigated extensively. This paper describes its application to brushless dc drives, and highlights the essential differences in its implementation, as regards torque ...
Howe, D., Liu, Y., Zhu, Z.Q.
core +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Analysis of Capacitor Ripple Current in Diesel Locomotive Auxiliary Converter
AC-DC-AC topology is commonly used in auxiliary converter module in diesel locomotive. In this paper, it assessed capacitor ripple current mathematical models in rectifier-side and inverter-side through Fourier spectrum, and put forward a calculation ...
FAN Wei, LUO Jianbo
doaj
Analytical evaluation of output current ripple amplitude in three-phase three-level inverters [PDF]
Nowadays, three-phase multilevel inverters are widely employed in medium and high-power applications, increasing the power ratings, improving the output voltage quality and reducing the conducted electromagnetic interferences.
Das S. +9 more
core +1 more source
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen +7 more
wiley +1 more source

