Results 161 to 170 of about 57,359 (285)

Senomorphic Small Extracellular Vesicles Delivered by a Tissue‐Adhesive α‐Lipoic‐Acid Hydrogel Enable Immuno‐Rejuvenation for Bone‐Tendon Interface Regeneration

open access: yesAdvanced Science, EarlyView.
This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong   +8 more
wiley   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Dynamic Supramolecular Polyurethane Elastomers Enabling Bioinspired Strain‐Adaptive Stiffening to Resolve the Softness–Strength Paradox

open access: yesAdvanced Science, EarlyView.
Segmental‐level molecular engineering of a supramolecular polyurethane elastomer integrates strain‐adaptive chains, soft elastic segments, and dynamic hydrogen bonding motifs. This design reconciles skin‐like softness with muscle‐level strength, offering a sustainable and high‐performance material platform for next‐generation artificial skin and soft ...
Haoming Zou   +5 more
wiley   +1 more source

Detecting clinically relevant topological structures in multiplexed spatial proteomics using TopKAT. [PDF]

open access: yesPatterns (N Y)
Samorodnitsky S   +6 more
europepmc   +1 more source

RIP

open access: yesEllipsis: A Journal of Art, Ideas, and Literature, 2016
openaire   +2 more sources

The Elephant Trunk Skin Inspires a Highly Sensitive and Deformable, Yet Robust, Armor Skin

open access: yesAdvanced Science, EarlyView.
The study presents the elephant trunk‐inspired armor skin with tactile sensing (ETATS). The ETATS architecture stretches and compresses while resisting puncture and tear, and it enables optical detection of pressure and lateral strain. Morphology‐based decoupling of strain and pressure paves the way to sensitive and deformable, yet robust, soft‐robotic
Jun Chang Yang   +3 more
wiley   +1 more source

Spinal Muscular Atrophy in Colombia: Nationwide Incidence, Demographic Distribution, and Healthcare Challenges. [PDF]

open access: yesCureus
Villamil-Osorio M   +4 more
europepmc   +1 more source

Toward Flexible Printed Electronics: A Spider‐Silk‐Inspired, Strong and Tough Thermoplastic Polyamide Elastomer

open access: yesAdvanced Science, EarlyView.
Inspired by spider silk, a bio‐inspired polyamide elastomer with a dynamic physical cross‐linking network is developed. Mimicking the rigid β‐sheet crystals and sacrificial hydrogen bonds of silk, the material achieves an exceptional balance of strength and toughness.
Bo Yang   +12 more
wiley   +1 more source

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