Results 171 to 180 of about 81,703 (295)

mRNA Decay Mediates Evolution and Biological Functions in Plant Gene Expression

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT mRNA decay is a key post‐transcriptional regulatory mechanism that fine‐tunes plant development and stress adaptation through dynamic mRNA stability control, bridging fundamental biology and crop improvement. Current knowledge of mRNA decay mechanisms in plants, largely derived from Arabidopsis, is poorly generalisable across plant lineages ...
Haidan Wu   +3 more
wiley   +1 more source

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild   +3 more
wiley   +1 more source

Circulating microRNA signatures reveal core and reversible dysregulation in obesity via machine learning

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Machine learning analysis of circulating microRNA (miRNA) profiles identified a minimal set of biomarkers that distinguish individuals with obesity from lean individuals both before and after weight‐loss intervention. Comparative analyses revealed heterogeneous molecular responses to weight reduction, with some miRNAs showing ...
Yuan Yue   +4 more
wiley   +1 more source

microRNA‐145‐5p regulates P‐glycoprotein and breast cancer resistance protein in primary human fetal brain endothelial cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Drug transporters P‐glycoprotein (P‐gp) and breast cancer resistance protein (BCRP) at the blood–brain barrier (BBB) protect the rapidly developing fetal brain. We investigated the role of microRNA‐145‐5p (miR‐145‐5p) microRNA (miRNA) in regulating these key transporters in primary human fetal brain endothelial cells in vitro. We
Phetcharawan Lye   +5 more
wiley   +1 more source

The Correlation of Psychological Symptoms, Quality of Life and Resilience in Patients with Recurrent Non-Melanoma Skin Cancer. [PDF]

open access: yesHealthcare (Basel)
Šimić G   +5 more
europepmc   +1 more source

Fault Diagnosis Method for DC Current Transformers Based on Deep Learning Hybrid Model

open access: yesVector: The Journal of Engineering, Volume 2027, Issue 1, January/December 2027.
Aiming at the problems of scarce fault samples, strong noise interference and complex feature coupling in the current DCCT fault diagnosis process, a DCCT fault diagnosis method based on a hybrid deep learning model is proposed. The performance of the proposed method is verified through experiments.
Cai Xu   +4 more
wiley   +1 more source

On‐Chip Learning With Crossbar Arrays for Adaptive Edge Intelligence

open access: yesAdvanced Computing, Volume 1, Issue 1, December 2026.
Memristor crossbar arrays implemented on chip combines memory, computation, and learning. They allow for adapting the neural weights using the incoming sensor data. This architecture reduces data movement leading to low‐latency, energy‐efficient intelligence in edge while being reliability‐aware co‐design across devices, circuits, and algorithms that ...
Alex James
wiley   +1 more source

Home - About - Disclaimer - Privacy