Results 211 to 220 of about 81,703 (295)

Design, Synthesis and Biophysical Characterisation of CPP‐PNA Conjugates for Targeting Oncogenic microRNA‐221

open access: yesJournal of Peptide Science, Volume 32, Issue 11, November 2026.
Cell‐penetrating peptide‐peptide nucleic acid (CPP‐PNA) conjugates that target the oncogenic microRNA‐221‐5p were synthesised using Cu(I)‐catalysed azide‐alkyne cycloaddition (CuAAC) and disulfide‐mediated conjugation strategies. These constructs form highly stable, sequence‐selective PNA/RNA heteroduplexes and demonstrate preliminary antiproliferative
Martina Rotondo   +3 more
wiley   +1 more source

ISA Support for Hardware Resource Partitioning in RISC-V

open access: yes
Heiser, Gernot   +9 more
core   +1 more source

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

open access: yesSmall, Volume 22, Issue 62, 6 November 2026.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo   +15 more
wiley   +1 more source

Long Non‐Coding RNAs: Key Regulators of Economic Traits in Livestock From Mechanisms to Breeding Applications

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Long non‐coding RNAs (lncRNAs) act as key regulators of economically important traits in livestock through diverse mechanisms including ceRNA networks, epigenetic regulation (X‐inactivation and imprinting) and liquid–liquid phase separation (LLPS).
Keyvan Khani   +2 more
wiley   +1 more source

tRNA‐Derived Small RNAs in Digestive Cancers: From Translational Regulation to Immune and Extracellular Communication

open access: yesCancer Science, Volume 117, Issue 11, Page 2924-2937, November 2026.
tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley   +1 more source

Home - About - Disclaimer - Privacy