Results 221 to 230 of about 81,703 (295)

Design to Dose: Integrating Quantitative Insights Across the Antibody Drug Conjugate (ADC) Development Lifecycle

Clinical and Translational Science, Volume 19, Issue 11, November 2026.
ABSTRACT Antibody‐drug conjugates (ADCs) are among the most pharmacologically complex therapeutics in clinical development. Their behavior emerges from the interplay of antibody disposition, linker stability, payload pharmacology, and host physiology—interdependencies that render qualitative descriptors such as “stronger affinity” or “more potent ...
Daniel Bending, Eshita Khera, Inez Lam, Innocent G. Asiimwe, Venkatesh Pilla Reddy   +4 more
wiley   +1 more source

A scalable security co-processor design for IoT applications. [PDF]

Sci Rep
Niazy M, Azmi H, Mahmoud MMA.
europepmc   +1 more source

Stress and Resilience Development in German Dental Students

European Journal of Dental Education, Volume 30, Issue 4, Page 1791-1798, November 2026.
ABSTRACT Introduction The study evaluated the effectiveness of a resilience training for dental students as a preventive measure for mental health and stress management, with consideration for its long‐term integration into dental education. Methods A 2‐day online resilience training was tailored to address specific stressors experienced by dental ...
Leonie X. Lin, Christine Keul, Martin R. Fischer, Jan Kiesewetter   +3 more
wiley   +1 more source

Prediction of risk of death in severely injured patients: the revised injury severity classification score, version 3 (RISC III). [PDF]

Eur J Trauma Emerg Surg
Lefering R, Imach S, Bieler D.
europepmc   +1 more source

Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress

Plant, Cell &Environment, Volume 49, Issue 11, Page 8437-8453, November 2026.
ABSTRACT Among various plant defence strategies, trichomes are tiny hair‐like structures on the epidermis that aid in defence, environmental adaptation and the production of valuable secondary metabolites. This review features trichomes as frontline guards for plant survival, integrating their structural, physiological and metabolic roles in ...
Debdatta Chatterjee, Madhabi Das, Sanjib Patra, Srijib Chatterjee, Amit Roy, Arunava Mandal   +5 more
wiley   +1 more source

4′‐ThioRNA Substitution and Sense‐Strand Segmentation for the Design of Functional Fully Modified siRNAs Targeting SARS‐CoV‐2

Chemistry – A European Journal, Volume 32, Issue 40, 27 October 2026.
4′‐ThioRNA was broadly tolerated across multiple positions in SARS‐CoV‐2‐targeting siRNAs, but full 4'‐thio modification of both strands caused a reduction in RNAi activity. Sense‐strand segmentation improved RNAi and antiviral activity, particularly when the nick was located at position 10 from the 5′‐end of the sense strand, thereby unlocking the ...
Yuhei Nogi, Jun Tsukimoto, Noriko Saito‐Tarashima, Takaaki Koma, Masako Nomaguchi, Noriaki Minakawa   +5 more
wiley   +1 more source

Structural basis for RISC assembly of human Argonaute2. [PDF]

Mol Cell
Zhang H, Adhav VA, Kehling AC, Savidge A, Shen Z, Fu TM, Nakanishi K.   +6 more
europepmc   +1 more source

Fluorene‐Framework Engineering Enables Narrowband Red Multi‐Resonance Emitters for High‐Efficiency With Negligible Roll‐Off Toward BT.2020

Angewandte Chemie, Volume 138, Issue 44, 26 October 2026.
σ‐Decoupled C9 fluorene‐framework topology control enables narrowband red MR emitters. SF‐BNO and PF‐BNO share the same BNO core, but differ in closed/open fluorene ring closure. SF‐BNO improves steric shielding and stability, while PF‐BNO enhances PLQY, orientation, and efficiency. Ex‐PSF and TE‐OLED architectures deliver ultra‐low efficiency roll‐off
Aradhya Rajput, Nisha Vergineya S, Subramanian Muruganantham, Meghana Tirupati, Odugu Pavan Kumar, Jun‐Yun Kim, Mi Young Chae, Jang Hyuk Kwon   +7 more
wiley   +1 more source

Interplay of singlet and triplet excited states in photoredox catalysis. [PDF]

Chem Sci
Bellatreccia C, Fina F, Ceroni P.
europepmc   +1 more source