Results 11 to 20 of about 2,472,934 (277)

A practical approach to communicating benefit-risk decisions of medicines to stakeholders [PDF]

open access: yesFrontiers in Pharmacology, 2015
PurposeThe importance of a framework for a systematic structured assessment of the benefits and risks has been established, but in addition, it is necessary that the benefit-risk decisions and the processes to derive those decisions are documented and ...
James eLeong   +3 more
doaj   +5 more sources

Breastfeeding during infancy and consumption of fish and dairy products are associated with chlorinated persistent organic pollutants in serum from Swedish adolescents

open access: yesEnvironmental Advances, 2022
Background: Food is considered the predominant source of human exposure to chlorinated and brominated persistent organic pollutants (POPs). Exposure and potential sources of these compounds are less studied in adolescents.
Galia Zamaratskaia   +6 more
doaj   +1 more source

The Nordic Nutrition Recommendations 2022 – food consumption and nutrient intake in the adult population of the Nordic and Baltic countries

open access: yesFood & Nutrition Research, 2022
Background: Knowledge about the nutrient intakes and food consumption in the Nordic and Baltic countries is important for the formulation of dietary reference values (DRVs) and food-based dietary guidelines (FBDGs), as part of the Nordic Nutrition ...
Eva Warensjö Lemming, Tagli Pitsi
doaj   +1 more source

Vitamin D status in children and adults in Sweden: dietary intake and 25-hydroxyvitamin D concentrations in children aged 10–12 years and adults aged 18–80 years

open access: yesJournal of Nutritional Science, 2020
The study aimed to estimate vitamin D intake and plasma/serum 25-hydroxyvitamin D (25(OH)D) concentrations, investigate determinants of 25(OH)D concentrations and compare two 25(OH)D assays.
Cecilia Nälsén   +6 more
doaj   +1 more source

A machine learning approach for identifying variables associated with risk of developing neutralizing antidrug antibodies to factor VIII

open access: yesHeliyon, 2023
A key unmet need in the management of hemophilia A (HA) is the lack of clinically validated markers that are associated with the development of neutralizing antibodies to Factor VIII (FVIII) (commonly referred to as inhibitors).
Atul Rawal   +5 more
doaj   +1 more source

Targeting mitochondrial quality control in muscle aging: Natural dietary products as potential interventions

open access: yesFood Frontiers, 2023
Mitochondria are the main sources of energy production for muscle tissues, including skeletal, cardiac, or smooth muscle, to support their activities.
Qi Chen   +4 more
doaj   +1 more source

Low concentrations of perfluoroalkyl acids (PFAAs) in municipal drinking water associated with serum PFAA concentrations in Swedish adolescents

open access: yesEnvironment International, 2023
While highly contaminated drinking water (DW) is a major source of exposure to perfluoroalkyl acids (PFAAs), the contribution of low-level contaminated DW (i.e. 
Jennifer Nyström-Kandola   +7 more
doaj   +1 more source

Riksmaten Adolescents 2016–17: A national dietary survey in Sweden – design, methods, and participation

open access: yesFood & Nutrition Research, 2018
Background: Nationally representative information on food consumption data is essential to evaluate dietary habits, inform policy-making and nutritional guidelines, as well as forming a basis for risk assessment and identification of risk groups ...
Lotta Moraeus   +5 more
doaj   +1 more source

Recommendations for benefit-risk assessment methodologies and visual representations. [PDF]

open access: yes, 2015
Purpose The purpose of this study is to draw on the practical experience from the PROTECT BR case studies and make recommendations regarding the application of a number of methodologies and visual representations for benefit–risk assessment.
Ashby, D   +15 more
core   +2 more sources

Patient-based benefit-risk assessment of medicines: development, refinement, and validation of a content search strategy to retrieve relevant studies

open access: yesJournal of the Medical Library Association, 2021
Introduction: Poor indexing and inconsistent use of terms and keywords may prevent efficient retrieval of studies on the patient-based benefit-risk assessment (BRA) of medicines.
Hiba El Masri   +5 more
doaj   +1 more source

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