Results 21 to 30 of about 7,404 (210)

Sexual function following risk-reducing salpingo-oophorectomy: a prospective cohort study. [PDF]

Sex Med
Abstract Background Increased access to and indications for genetic testing will lead to more women undergoing risk-reducing salpingo-oophorectomy (RRSO), with a potential impact on sexual function.
von Kartaschew ÅE, Hirschberg AL, Gemzell-Danielsson K, Flöter Rådestad A.   +3 more
europepmc   +3 more sources

Decisional conflict in women with a BRCA1 or BRCA2 pathogenic variant who have not elected for risk-reducing salpingo-oophorectomy [PDF]

Hereditary Cancer in Clinical Practice
Objective To identify predictors of decisional conflict among women with a BRCA pathogenic variant (PV) who were eligible for risk reducing salpingo-oophorectomy (RRSO) who had not made a decision to have surgery at least one year after receiving genetic
Kelly A. Metcalfe, Anita Y. Kinney, Steven A. Narod, Aletta Poll, Susan Armel, Lucia Lombardi, Farideh Tavangar, Tuya Pal   +7 more
doaj   +2 more sources

Risk-reducing salpingo-oophorectomy among diverse patients with BRCA mutations at an urban public hospital: a mixed methods study [PDF]

BMJ Open
Objectives To assess the association of socioeconomic demographics with recommendation for and uptake of risk-reducing bilateral salpingo-oophorectomy (rrBSO) in patients with BRCA1 and BRCA2 (BRCA1/2) mutations.Design Retrospective cohort ...
Kent Hoskins, Tara Maga, Shannon MacLaughlan David, Nicole Lugo Santiago, Alexandra J Lamacki, Sandra Spychalska, Lara Balay, Kimberly Richardson, Quetzal A Class   +8 more
doaj   +2 more sources

Feasibility of risk reducing salpingo-oophorectomy at the time of abdominal surgery for correction of pelvic organ prolapse and urinary incontinence [PDF]

Gynecology and Minimally Invasive Therapy, 2021
Objective: The objective of this study is to assess the perioperative outcomes when prophylactic bilateral salpingo-oophorectomy (BSO) is performed concomitantly with surgery to repair pelvic organ prolapse (POP) or stress urinary incontinence (SUI ...
Ali Azadi, James A Bradley, Greg J Marchand, Douglas J Lorenz, David Doering, Donald R Ostergard   +5 more
doaj   +2 more sources

Utility Scores for Risk-Reducing Mastectomy and Risk-Reducing Salpingo-Oophorectomy: Mapping to EQ-5D. [PDF]

Cancers (Basel)
Background: Risk-reducing mastectomy (RRM) and risk-reducing salpingo-oophorectomy (RRSO) are the most effective breast and ovarian cancer preventive interventions. EQ-5D is the recommended tool to assess the quality of life and determine health-related utility scores (HRUSs), yet there are no published EQ-5D HRUSs after these procedures.
Oxley SG, Wei X, Sideris M, Blyuss O, Kalra A, Sia JJY, Ganesan S, Fierheller CT, Sun L, Sadique Z, Jin H, Manchanda R, Legood R.   +12 more
europepmc   +5 more sources

Risk-Reducing Options for High-Grade Serous Gynecologic Malignancy in BRCA1/2

Current Oncology, 2022
Ovarian cancer (OC) is the leading cause of death among women with gynecologic malignancy. Breast Cancer Susceptibility Gene 1 (BRCA 1) and Breast Cancer Susceptibility Gene 2 (BRCA 2) germline mutations confer an estimated 20 to 40 times increased risk ...
Lauren Clarfield, Laura Diamond, Michelle Jacobson   +2 more
doaj   +1 more source

Quality of life after risk-reducing surgery for breast and ovarian cancer prevention: a systematic review and meta-analysis. [PDF]

, 2023
OBJECTIVE: This study aimed to assess the impact of risk-reducing surgery for breast cancer and ovarian cancer prevention on quality of life. We considered risk-reducing mastectomy, risk-reducing salpingo-oophorectomy, and risk-reducing early ...
Brentnall, A, Kalra, A, Legood, R, Manchanda, R, Oxley, S, Sideris, M, Sun, L, Wei, X, Yang, L   +8 more
core   +2 more sources

Effectiveness of Secondary Risk–Reducing Strategies in Patients With Unilateral Breast Cancer With Pathogenic Variants of BRCA1 and BRCA2 Subjected to Breast-Conserving Surgery: Evidence-Based Simulation Study

JMIR Formative Research, 2022
BackgroundApproximately 62% of patients with breast cancer with a pathogenic variant (BRCA1 or BRCA2) undergo primary breast-conserving therapy.
Jelena Maksimenko, Pedro Pereira Rodrigues, Miki Nakazawa-Miklaševiča, David Pinto, Edvins Miklaševičs, Genadijs Trofimovičs, Jānis Gardovskis, Fatima Cardoso, Maria João Cardoso   +8 more
doaj   +1 more source

Subjective cognitive changes following premenopausal risk-reducing bilateral salpingo-oophorectomy

Climacteric, 2023
Women at high risk of ovarian cancer are commonly advised to undergo risk-reducing bilateral salpingo-oophorectomy (BSO) prior to natural menopause. Cognitive symptoms during natural menopause transition are frequently reported; however, very few studies have examined cognitive changes following surgical menopause.
A. Ramachandra, E. H. X. Thomas, A. J. Vincent, M. Hickey, N. Warren, J. Kulkarni, L. E. Forrest, J. Bojadzieva, A. Campbell, C. Gurvich   +9 more
openaire   +2 more sources

Prophylactic Mastectomy and Salpingo-Oophorectomy: Ethics and Policy

Middle East Journal of Cancer, 2020
Breast cancer is the most common cancer and the fifth most common cause of death from cancer in women. Ovarian cancer is the deadliest type of the gynecological cancers.
Majd T. Mrayyan, Marwan Shawish
doaj   +1 more source