Results 31 to 40 of about 7,404 (210)
The impact of risk-reducing salpingo-oophorectomy
The idea of this thesis was formed on the basis of the expected disruption of quality of life in women choosing risk-reducing salpingo-oophorectomy (RRSO) as prevention strategy. In the search for the consequences of RRSO on menopausal symptoms, sexuality, depression and anxiety, osteoporosis, mental health and cardiovascular health, information ...
openaire +4 more sources
Summary: Background: This study aimed to compare the quality of life (QOL), psychosocial status, sexual function, and menopausal symptoms between the risk-reducing salpingo-oophorectomy (RRSO) and non-RRSO groups comprising BRCA mutation carriers and to
Sumin Chae +10 more
doaj +1 more source
Factors influencing uptake and timing of risk reducing salpingo-oophorectomy in women at risk of familial ovarian cancer: a competing risk time to event analysis [PDF]
Objective To evaluate factors affecting uptake of risk-reducing salpingo-oophorectomy (RRSO) over time in women at high-risk of familial ovarian cancer. Design Prospective observational cohort.
Antill +42 more
core +1 more source
Prophylactic bilateral salpingo-oophorectomy (PBSO) is regularly performed when patients have a high risk of developing ovarian cancer (i.e. a personal or family history).
Sophia Halassy +3 more
doaj +1 more source
Adjuvant radiotherapy for primary breast cancer in BRCA1 and BRCA2 mutation carriers and risk of contralateral breast cancer with special attention to patients irradiated at younger age [PDF]
The purpose of this study was to estimate the influence of adjuvant radiotherapy for primary breast cancer (BC) on the risk of contralateral BC (CBC) in BRCA1 or BRCA2(BRCA1/2) mutation carriers, with special attention to patients irradiated at age ...
A Mislowsky +39 more
core +13 more sources
Risk Reducing Salpingectomy and Delayed Oophorectomy in high risk women: views of cancer geneticists, genetic counsellors and gynaecological oncologists in the UK [PDF]
Risk-reducing-salpingectomy and Delayed-Oophorectomy (RRSDO) is being proposed as a two-staged approach in place of RRSO to reduce the risks associated with premature menopause in high-risk women.
A Antoniou +61 more
core +3 more sources
Loss of heterozygosity in the SMARCA4 gene is a hallmark feature of small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), an aggressive ovarian cancer occurring in young adults and adolescents with an average age of 23 years and a median ...
John A. Vu +7 more
doaj +1 more source
Diathermy-Induced Injury May Affect Detection of Occult Tubal Lesions at Risk-Reducing Salpingo-Oophorectomy [PDF]
Background: Electrosurgery-induced tubal thermal injury obscures cellular detail and hampers histomorphological assessment for occult pathology. Objective: The objectives of this study were to report on diathermy-related thermal injuries to the fallopian
Adam N. Rosenthal +43 more
core +1 more source
We assessed the prevalence, localization, type and outcome of occult cancer at risk-reducing salpingo-oophorectomy or salpingectomy (RRSO) in asymptomatic carriers of pathogenic or likely pathogenic BRCA1/2 variants and high-risk BRCA1/2 negative women.
Gornjec Andreja +7 more
doaj +1 more source
Fertility preservation in ovarian tumours [PDF]
A considerable number of patients with a cancer diagnosis are of childbearing age and have not satisfied their desire for a family. Despite ovarian cancer (OC) usually occurring in older patients, 3%–14% are diagnosed at a fertile age with the overall 5 ...
Bardhi, E. +8 more
core +1 more source

