Relationship satisfaction predicts sexual activity following risk-reducing salpingo-oophorectomy [PDF]
Changes in sexual function are a common outcome following risk-reducing salpingo-oophorectomy (RRSO), a prophylactic surgery for women at high risk of ovarian and other gynecologic cancers. Despite the known importance of sexuality in patients' quality of life and satisfaction with surgery, little is known about what predicts sexual activity following ...
Tierney, Lorenz +2 more
openaire +2 more sources
Cost-effectiveness of Population Screening for BRCA Mutations in Ashkenazi Jewish Women Compared With Family History-Based Testing [PDF]
BACKGROUND: Population-based testing for BRCA1/2 mutations detects the high proportion of carriers not identified by cancer family history (FH)-based testing.
Abdel-Rahman +132 more
core +4 more sources
Background In Japan, genetic testing, surveillance, and risk-reducing surgery for hereditary breast and ovarian cancer (HBOC) syndrome have been covered by the Japanese national insurance system since April 2020.
Aya Tanaka +9 more
doaj +1 more source
Primary Peritoneal Cancer Two Decades after a Bilateral Salpingo-Oophorectomy
Bilateral salpingo-oophorectomy (BSO) is increasingly employed as a risk-reducing strategy for epithelial ovarian cancer (EOC). We report the third case of a patient developing primary peritoneal cancer two decades after a bilateral salpingo-oophorectomy.
Melinda Rodowa +2 more
doaj +1 more source
Use of hormone replacement therapy after risk‐reducing salpingo‐oophorectomy [PDF]
AbstractIntroductionAfter premenopausal risk‐reducing salpingo‐oophorectomy (RRSO) to prevent ovarian cancer, the non‐cancer‐related morbidity and mortality may be increased if sex hormones are not replaced. Several guidelines recommend systemic hormone replacement therapy (HRT) to these women until the expected age of menopause.
Nora Johansen +5 more
openaire +2 more sources
Background The effect of risk-reducing salpingo-oophorectomy (RRSO) on breast cancer risk for BRCA1 and BRCA2 mutation carriers is uncertain. Retrospective analyses have suggested a protective effect but may be substantially biased.
Nasim Mavaddat +62 more
doaj +1 more source
Hereditary Women’s Cancer: Management and Risk-Reducing Surgery
Hereditary women’s syndromes due to inherited mutations result in an elevated risk of developing gynecological cancers over the lifetime of affected carriers.
Carmine Conte +9 more
doaj +1 more source
Understanding the Needs of Women Considering Risk-Reducing Salpingo-oophorectomy [PDF]
Because of the significantly increased lifetime risk of ovarian cancer associated with inheritance of a germline mutation in the BRCA1/2 genes, women with a deleterious mutation are recommended to undergo risk-reducing salpingo-oophorectomy at age 35 years or once child-bearing is complete.
Carol, Cherry +4 more
openaire +2 more sources
Specifying the ovarian cancer risk threshold of 'premenopausal risk-reducing salpingo-oophorectomy' for ovarian cancer prevention: a cost-effectiveness analysis [PDF]
BACKGROUND: Risk-reducing salpingo-oophorectomy (RRSO) is the most effective intervention to prevent ovarian cancer (OC). It is only available to high-risk women with >10% lifetime OC risk.
Antoniou, AC +4 more
core +1 more source
What Have We Learned from Risk-Reducing Salpingo-oophorectomy? [PDF]
In this issue of the Journal, Rebbeck et al. (1) have provided us with a meticulously executed, up-to-date meta-analysis that quantifies the reductions in the risks of breast and ovarian/fallopian tube cancer that follow risk-reducing salpingo-oophorectomy (RRSO) in BRCA1 and BRCA2 (BRCA1/2) mutation carriers.
M. H. Greene, P. L. Mai
openaire +1 more source

