Results 51 to 60 of about 7,404 (210)
Frontiers in Oncology, 2014 Risk-reducing bilateral salpingo-oophorectomy is a proven strategy to reduce the risk of serous ovarian cancer associated with germline BRCA mutations.
Tess eSchenberg +2 more
doaj +1 more source
Advances in Tumor Screening, Imaging, and Avatar Technologies for High-Grade Serous Ovarian Cancer [PDF]
, 2014 The majority of high-grade serous ovarian carcinoma cases are detected in advanced stages when treatment options are limited. Surgery is less effective at eradicating the disease when it is widespread, resulting in high rates of disease relapse and ...
Dinulescu, Daniela M. +2 more
core +2 more sources
World Journal of Surgical Oncology, 2017 Background Risk-reducing bilateral salpingo-oophorectomy (RRBSO) increases survival in patients at high risk of developing ovarian cancer. While many general gynecologists perform this procedure, some argue it should be performed exclusively by ...
Dominique R. Malacarne +3 more
doaj +1 more source
Ovarian cancer arising from the proximal fallopian tube in a patient with a BRCA2 mutation
Gynecologic Oncology Reports, 2021 Patients with BRCA mutations are at high risk of high grade serous ovarian cancer. A paradigm shift has resulted in the current understanding that many cases of ovarian cancer actually arise from the fimbriated fallopian tube.
Nora Badiner +3 more
doaj +1 more source
Fertility preservation in gynaecologic cancers [PDF]
, 2018 Due to substantial improvement in the diagnosis and treatment of gynaecologic cancers, a better understanding of patient care needs to be revised. We reviewed the literature related to fertility preservation strategies in gynaecological cancer and ...
De Felice, Francesca +9 more
core +1 more source
Gynecologic Oncology Reports, 2023 Objectives: Bilateral salpingo-oophorectomy (BSO) is recommended to reduce the risk of ovarian cancer in patients with high-risk germline mutations, but the resultant surgical menopause can lead to detrimental health effects and impact quality of life ...
Talayeh Ghezelayagh +7 more
doaj +1 more source
Factors Influencing Uptake of Risk-Reducing Salpingo-Oophorectomy by BRCA1 and BRCA2 Mutation Carriers [PDF]
, 2016 Germline mutations in the BRCA1 and BRCA2 genes are associated with significantly increased risks for ovarian cancer. The National Comprehensive Cancer Network (NCCN) currently recommends that female BRCA mutation carriers undergo risk-reducing salpingo ...
Breen, Victoria E
core +1 more source
Hereditary ovarian cancer [PDF]
, 2009 Apoptosis is a form of cell death that permits the removal of damaged, senescent or unwanted cells in multicellular organisms, without damage to the cellular microenvironment.
BAZAN, Viviana +5 more
core +1 more source
Advanced Science, EarlyView.This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia +6 more
wiley +1 more source
Hereditary Cancer in Clinical Practice, 2019 Background Little is known about the status of genetic counseling for ovarian cancer in China. Case presentation We report a four-generation Chinese family with several types of cancer.
Wenhui Li, Lei Li, Ming Wu
doaj +1 more source