Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Escalating risk-taking is linked to emotional habituation. [PDF]
Haj-Ali H, Glickman M, Sharot T.
europepmc +1 more source
Investor Protection and Income Inequality: Risk Sharing vs Risk Taking [PDF]
This paper studies the relationship between investor protection, entrepreneurial risk taking and income inequality. In the presence of market frictions, better protection makes investors more willing to take on entrepreneurial risk when lending to firms,
Alessandra Bonfiglioli
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Chimpanzee locomotor risk-taking points to the importance of parental and alloparental supervision in humans. [PDF]
Murray B, MacLatchy L, Sarringhaus L.
europepmc +1 more source
Nucleus accumbens activation mediates the influence of reward cues on financial risk-taking [PDF]
In functional magnetic resonance imaging (FMRI) research, nucleus accumbens (NAcc) activation spontaneously increases prior to financial risk taking.
Knutson, Brian +3 more
core +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
General risk preference comes up short when predicting risk-taking frequency. [PDF]
Asp M, Abed M, Millroth P.
europepmc +1 more source
Life Below Zero: Negative Policy Rates and Bank Risk Taking
Florian Heider +2 more
openalex +1 more source

